Fragrant olive (Osmanthus fragrans Lour.) flower extract attenuates dexamethasone-induced muscle atrophy through stimulation of PI3K/Akt pathway in C2C12 myotubes and C57BL/6 mice

Fragrant olive (Osmanthus fragrans Lour.) flower extract attenuates dexamethasone-induced muscle atrophy through stimulation of PI3K/Akt pathway in C2C12 myotubes and C57BL/6 mice

Maintaining protein homeostasis is crucial to prevent muscle wasting caused by an imbalance between muscle protein synthesis and degradation. In this study, in vitro and in vivo experiments were performed using C2C12 myotubes and C57BL/6 mice treated with dexamethasone to investigate the anti-atroph...

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Bibliographic Details
Main Authors: Taeuk Kim, Seungok Lee, Sein Lee, Hyejung Han, Chul-Hong Kim, Dong-Woo Lee, Jae-Kwan Hwang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Functional Foods
Subjects:
Osmanthus fragrans
Fragrant olive
Dexamethasone
Muscle atrophy
PI3K/Akt
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464625000362
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