Global, Regional, and National Burden of Ectopic Pregnancy: A 30-Year Observational Database Study
Objective. To estimate global, regional, and national trends due to ectopic pregnancy as part of the 2019 Global Burden of Disease study. Methods. We systematically reviewed trends in ectopic pregnancy burden using data from the Global Burden of Disease (GBD) database, including 21 regions, 195 coun...
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Wiley
2023-01-01
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| Series: | International Journal of Clinical Practice |
| Online Access: | http://dx.doi.org/10.1155/2023/3927337 |
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| author | Wang Bo Zhang Qianyu Li Mo |
| author_facet | Wang Bo Zhang Qianyu Li Mo |
| author_sort | Wang Bo |
| collection | DOAJ |
| description | Objective. To estimate global, regional, and national trends due to ectopic pregnancy as part of the 2019 Global Burden of Disease study. Methods. We systematically reviewed trends in ectopic pregnancy burden using data from the Global Burden of Disease (GBD) database, including 21 regions, 195 countries, and territories over the past 30 years. The trends of ectopic pregnancy-related incidence, mortality, and disability-adjusted life years (DALYs) attributable to all known risk factors were also analyzed. Age-standardized rates (ASRs) and their estimated annual percentage changes (EAPCs) were also calculated. Results. Incident cases, deaths, and DALYs of ectopic pregnancy increased worldwide in the past 30 years. The age-standardized incidence rate (ASIR) was decreasing (EAPC = −1.14, 95% confidence interval (CI): −1.29 to −0.98), and the age-standardized death (EAPC = −0.9, 95% CI: −1.03 to −0.76) and DALY rate decreased generally (EAPC = −0.83, 95% CI: −0.98 to −0.68). In addition, the burden of ectopic pregnancy is lower in areas with higher socioeconomic development, and significant positive correlations between ASRs and sociodemographic index (SDI) were observed, especially among low-middle SDI, and low SDI quintiles carried the majority burden of ectopic pregnancy. Conclusion. Globally, the incidence, mortality, and DALY rate of ectopic pregnancy had been decreasing from 1990 to 2019. Compared with lower and decreasing ASIR in the high SDI region, ASIR in the low SDI region was always high, indicating the need for ectopic pregnancy treatment improvement and the establishment of more targeted and specific strategies in low SDI countries to reduce the incidence of ectopic pregnancy. |
| format | Article |
| id | doaj-art-0da4e1906ade47318c6600235994ea84 |
| institution | OA Journals |
| issn | 1742-1241 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
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| series | International Journal of Clinical Practice |
| spelling | doaj-art-0da4e1906ade47318c6600235994ea842025-08-20T02:02:39ZengWileyInternational Journal of Clinical Practice1742-12412023-01-01202310.1155/2023/3927337Global, Regional, and National Burden of Ectopic Pregnancy: A 30-Year Observational Database StudyWang Bo0Zhang Qianyu1Li Mo2Department of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyObjective. To estimate global, regional, and national trends due to ectopic pregnancy as part of the 2019 Global Burden of Disease study. Methods. We systematically reviewed trends in ectopic pregnancy burden using data from the Global Burden of Disease (GBD) database, including 21 regions, 195 countries, and territories over the past 30 years. The trends of ectopic pregnancy-related incidence, mortality, and disability-adjusted life years (DALYs) attributable to all known risk factors were also analyzed. Age-standardized rates (ASRs) and their estimated annual percentage changes (EAPCs) were also calculated. Results. Incident cases, deaths, and DALYs of ectopic pregnancy increased worldwide in the past 30 years. The age-standardized incidence rate (ASIR) was decreasing (EAPC = −1.14, 95% confidence interval (CI): −1.29 to −0.98), and the age-standardized death (EAPC = −0.9, 95% CI: −1.03 to −0.76) and DALY rate decreased generally (EAPC = −0.83, 95% CI: −0.98 to −0.68). In addition, the burden of ectopic pregnancy is lower in areas with higher socioeconomic development, and significant positive correlations between ASRs and sociodemographic index (SDI) were observed, especially among low-middle SDI, and low SDI quintiles carried the majority burden of ectopic pregnancy. Conclusion. Globally, the incidence, mortality, and DALY rate of ectopic pregnancy had been decreasing from 1990 to 2019. Compared with lower and decreasing ASIR in the high SDI region, ASIR in the low SDI region was always high, indicating the need for ectopic pregnancy treatment improvement and the establishment of more targeted and specific strategies in low SDI countries to reduce the incidence of ectopic pregnancy.http://dx.doi.org/10.1155/2023/3927337 |
| spellingShingle | Wang Bo Zhang Qianyu Li Mo Global, Regional, and National Burden of Ectopic Pregnancy: A 30-Year Observational Database Study International Journal of Clinical Practice |
| title | Global, Regional, and National Burden of Ectopic Pregnancy: A 30-Year Observational Database Study |
| title_full | Global, Regional, and National Burden of Ectopic Pregnancy: A 30-Year Observational Database Study |
| title_fullStr | Global, Regional, and National Burden of Ectopic Pregnancy: A 30-Year Observational Database Study |
| title_full_unstemmed | Global, Regional, and National Burden of Ectopic Pregnancy: A 30-Year Observational Database Study |
| title_short | Global, Regional, and National Burden of Ectopic Pregnancy: A 30-Year Observational Database Study |
| title_sort | global regional and national burden of ectopic pregnancy a 30 year observational database study |
| url | http://dx.doi.org/10.1155/2023/3927337 |
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