Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation

Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation

Saved in:

Bibliographic Details
Main Authors:	Linn S. M. Evenseth, Clizia Russotto, Imin Wushur, Dawid Warszycki, Angel S. Moldes-Anaya, Andrzej J. Bojarski, Mari Gabrielsen, Ingebrigt Sylte
Format:	Article
Language:	English
Published:	American Chemical Society 2025-05-01
Series:	ACS Omega
Online Access:	https://doi.org/10.1021/acsomega.5c02102
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Co-folding, the future of docking – prediction of allosteric and orthosteric ligands
by: Eva Nittinger, et al.
Published: (2025-12-01)

Orthosteric STING inhibition elucidates molecular correction of SAVI STING
by: Tao Xie, et al.
Published: (2025-07-01)

Interactions of substrates and phosphinyl containing inhibitors with bacterial and human zinc proteases.
by: Fatema Amatur Rahman, et al.
Published: (2025-01-01)

GABAB Receptor: Structure, Biological Functions, and Therapy for Diseases
by: Weijie Xie, et al.
Published: (2025-05-01)

FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists.
by: Danijela Markovic, et al.
Published: (2012-01-01)

Genetic implication of GABAB receptors in the etiology of neurological and psychiatric disorders
by: Martin Gassmann, et al.
Published: (2025-07-01)

Effect of GABAB Receptor Antagonist (CGP35348) on Learning and Memory in Albino Mice
by: Quratulane Gillani, et al.
Published: (2014-01-01)

Phylogenetic divergence of GABAB receptor signaling in neocortical networks over adult life
by: Max A. Wilson, et al.
Published: (2025-05-01)

Level of M1 GABAB predicts micro offline consolidation of motor learning during wakefulness
by: Pasquale Cardellicchio, et al.
Published: (2025-02-01)

Positive Anti-GABAB Receptor Antibodies in a Patient with Hashimoto’s Thyroiditis and Bipolar Affective Disorder
by: Polina A. Sobolevskaia, et al.
Published: (2021-10-01)

GABAB receptor activation contributes to post-surgery cognitive impairments in mice by inducing hippocampal BDNF hypermethylation
by: Tong Wu, et al.
Published: (2025-12-01)

Action of GABAB receptor on local network oscillation in somatosensory cortex of oral part: focusing on NMDA receptor
by: Hiroyuki Kanayama, et al.
Published: (2024-03-01)

Role of Rab10 in cocaine-induced behavioral effects is associated with GABAB receptor membrane expression in the nucleus accumbens
by: Zhuoxuan Yu, et al.
Published: (2024-11-01)

Systemic corticosterone enhances fear memory extinction in rats: Involvement of the infralimbic medial prefrontal cortex GABAA and GABAB receptors
by: Samira Omoumi, et al.
Published: (2024-10-01)

Activation of GABAB Receptor Suppresses Diabetic Neuropathic Pain through Toll-Like Receptor 4 Signaling Pathway in the Spinal Dorsal Horn
by: Peng Liu, et al.
Published: (2018-01-01)

Optimization of neuron-specific interfering peptides targeting GABAB receptor downregulation for proteolytic stability for conferring neuroprotection in a mouse model of cerebral ischemia
by: Mohammad Hleihil, et al.
Published: (2025-04-01)

The E3 ubiquitin ligase MARCH1 mediates downregulation of plasma membrane GABAB receptors under ischemic conditions by inhibiting fast receptor recycling
by: Musadiq A. Bhat, et al.
Published: (2025-01-01)

Ligand-Based Virtual Screening Using Bayesian Inference Network and Reweighted Fragments
by: Ali Ahmed, et al.
Published: (2012-01-01)

Structure- and Ligand-Based Virtual Screening for Identification of Novel TRPV4 Antagonists
by: Atefeh Saadabadi, et al.
Published: (2024-12-01)

Margherita Zalum Cardon, Passione e cultura dei fiori tra Firenze e Roma nel XVI e XVII secolo
by: Clizia Magoni
Published: (2010-01-01)

Novel 3-Ethoxysalicylaldehyde Lanthanide Complexes Obtained by Decomposition of <i>Salen</i>-Type Ligands
by: Paula Mediavilla, et al.
Published: (2025-03-01)

Virtual Screening Approaches to Identify Promising Multitarget-Directed Ligands for the Treatment of Autism Spectrum Disorder
by: Jakub Jończyk, et al.
Published: (2024-11-01)

“It was a real wake-up call for the pupils.”
by: Anja Gabrielsen, et al.
Published: (2025-04-01)

Vold mod politiet?
by: Gorm Gabrielsen
Published: (1987-01-01)

G. Foti-Talamanca, Ricerche sul processo nell-Egitto Greco-Romano, II. L'introduzione del giudizio
by: Władysław Bojarski
Published: (1983-05-01)

Władysław Rozwadowski, Prawo rzymskie. Zarys wykładu wraz z wyborem źródeł, wyd. 2, 1992
by: Władysław Bojarski
Published: (1992-12-01)

Rola sektora publicznego w rozwoju budownictwa mieszkaniowego
by: Włodzimierz Bojarski
Published: (2006-01-01)

Działalność prawotwórcza Ministerstwa byłej Dzielnicy Pruskiej w sprawach wojskowych
by: Adam Bojarski
Published: (2025-06-01)

Sądownictwo specjalne powołane przez ministra byłej dzielnicy pruskiej w 1920 roku
by: Adam Bojarski
Published: (2020-08-01)

Prawo łaski stosowane przez Naczelnika Państwa Józefa Piłsudskiego w byłym zaborze pruskim w latach 1919–1922 w świetle zachowanych akt Archiwum Akt Nowych w Warszawie
by: Adam Bojarski
Published: (2021-06-01)

Lineamenti di storia del diritto romano. Sotto la direzione di M. Talamanca
by: Władysław Bojarski
Published: (1983-05-01)

Reseña. "Maletas de cartón. 50 años de emigración española a Alemania (1960 – 2010).
by: Rocio Moldes Farelo
Published: (2019-09-01)

Reseña. "Maletas de cartón. 50 años de emigración española a Alemania (1960 – 2010).
by: Rocio Moldes Farelo
Published: (2019-09-01)

E-sports y brecha de género: La percepción de las profesionales españolas
by: Rocío Moldes Farelo
Published: (2024-07-01)

Identification of a Non-Retinoid Opsin Ligand Through Pharmacophore-Guided Virtual Screening—A Novel Potential Rhodopsin-Stabilizing Compound
by: Miriana Di Stefano, et al.
Published: (2025-05-01)

Lenguaje de Programación Cubano para los niveles de enseñanza primaria, secundaria y media
by: Addiel Alejandro Moldes González
Published: (2023-12-01)

Digitalización de la libreta de abastecimiento
by: Addiel Alejandro Moldes González
Published: (2023-02-01)

Bluues_cplx: Electrostatics at Protein–Protein and Protein–Ligand Interfaces
by: Miguel Angel Soler, et al.
Published: (2025-01-01)

Naturen som læringsarena i norsk grunnskole
by: Majken Korsager, et al.
Published: (2024-12-01)

Det stigende antal retspsykiatriske patienter
by: Gorm Gabrielsen, et al.
Published: (2007-11-01)