Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation

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Main Authors: Linn S. M. Evenseth, Clizia Russotto, Imin Wushur, Dawid Warszycki, Angel S. Moldes-Anaya, Andrzej J. Bojarski, Mari Gabrielsen, Ingebrigt Sylte
Format: Article
Language:English
Published: American Chemical Society 2025-05-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.5c02102
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author Linn S. M. Evenseth
Clizia Russotto
Imin Wushur
Dawid Warszycki
Angel S. Moldes-Anaya
Andrzej J. Bojarski
Mari Gabrielsen
Ingebrigt Sylte
author_facet Linn S. M. Evenseth
Clizia Russotto
Imin Wushur
Dawid Warszycki
Angel S. Moldes-Anaya
Andrzej J. Bojarski
Mari Gabrielsen
Ingebrigt Sylte
author_sort Linn S. M. Evenseth
collection DOAJ
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id doaj-art-0d9c0a790d1a4f2ba64485c3aabb1fbb
institution DOAJ
issn 2470-1343
language English
publishDate 2025-05-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-0d9c0a790d1a4f2ba64485c3aabb1fbb2025-08-20T03:07:35ZengAmerican Chemical SocietyACS Omega2470-13432025-05-011021220052201710.1021/acsomega.5c02102Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro ValidationLinn S. M. Evenseth0Clizia Russotto1Imin Wushur2Dawid Warszycki3Angel S. Moldes-Anaya4Andrzej J. Bojarski5Mari Gabrielsen6Ingebrigt Sylte7Pharmacology and Toxicology, Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, NorwayPharmacology and Toxicology, Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, NorwayPharmacology and Toxicology, Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, NorwayDepartment of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, PolandCyclotron and Radiochemistry Unit, Section for Radiopharmaceutical Production, The PET Imaging Center, University Hospital of North Norway (UNN), Tromsø, NorwayDepartment of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, PolandPharmacology and Toxicology, Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, NorwayPharmacology and Toxicology, Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norwayhttps://doi.org/10.1021/acsomega.5c02102
spellingShingle Linn S. M. Evenseth
Clizia Russotto
Imin Wushur
Dawid Warszycki
Angel S. Moldes-Anaya
Andrzej J. Bojarski
Mari Gabrielsen
Ingebrigt Sylte
Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation
ACS Omega
title Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation
title_full Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation
title_fullStr Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation
title_full_unstemmed Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation
title_short Identification of Orthosteric GABAB Receptor Ligands by Virtual Screening and In Vitro Validation
title_sort identification of orthosteric gabab receptor ligands by virtual screening and in vitro validation
url https://doi.org/10.1021/acsomega.5c02102
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