Association Between Endothelial Alterations, Cardiac Function, and Outcomes From Health to Heart Failure: Insight From the STANISLAS, MEDIA‐DHF, and BIOSTAT‐CHF Cohorts

Association Between Endothelial Alterations, Cardiac Function, and Outcomes From Health to Heart Failure: Insight From the STANISLAS, MEDIA‐DHF, and BIOSTAT‐CHF Cohorts

Background Heart failure with preserved ejection fraction (HFpEF) is a multifaceted syndrome, likely stemming from comorbidity‐induced inflammation resulting in endothelial dysfunction. Endothelial glycocalyx degradation's role in the development and prognosis of HFpEF remains largely unexplore...

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Bibliographic Details
Main Authors: Jeremy Lagrange, Mohammad Jahangiri, Guillaume Baudry, Nathalie Mercier, Luca Monzo, Zohra Lamiral, Kévin Duarte, Jozine M ter Maaten, Faiez Zannad, Adriaan A. Voors, Nicolas Girerd
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
endothelial cells
glycocalyx
heart failure with preserved ejection fraction
perlecan
thrombomodulin
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.040179
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