Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature

Extranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non-Hodgkin lymphoma and has a constant association with Epstein-Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero-digestive tract, of which stomach is a very rare site. Very few cases...

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Main Authors: Prashant Mane, Prashant Ramteke, Anand Singh, Ajay Gogia, Saumyaranjan Mallick
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-04-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:https://journals.lww.com/10.4103/ijpm.ijpm_32_22
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author Prashant Mane
Prashant Ramteke
Anand Singh
Ajay Gogia
Saumyaranjan Mallick
author_facet Prashant Mane
Prashant Ramteke
Anand Singh
Ajay Gogia
Saumyaranjan Mallick
author_sort Prashant Mane
collection DOAJ
description Extranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non-Hodgkin lymphoma and has a constant association with Epstein-Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero-digestive tract, of which stomach is a very rare site. Very few cases of gastric extranodal NK/T cell lymphoma have been reported in the literature. A 22-year-old male patient presented with complaints of abdominal pain and hematemesis. Endoscopy showed a large ulcer in the stomach. Partial gastrectomy done and histopathology showed transmural infiltration by intermediate size atypical lymphoid cells which are immunopositive for CD3, CD56, TIA, EBV-encoded RNA (EBER) and negative for CD4, CD8, CD20. A diagnosis of extranodal NK/T cell lymphoma nasal type was made.
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institution Kabale University
issn 0377-4929
0974-5130
language English
publishDate 2024-04-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Pathology and Microbiology
spelling doaj-art-0d983621bb6a4504b2edd67ccaad433a2025-02-07T14:01:49ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-04-01Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literaturePrashant ManePrashant RamtekeAnand SinghAjay GogiaSaumyaranjan MallickExtranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non-Hodgkin lymphoma and has a constant association with Epstein-Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero-digestive tract, of which stomach is a very rare site. Very few cases of gastric extranodal NK/T cell lymphoma have been reported in the literature. A 22-year-old male patient presented with complaints of abdominal pain and hematemesis. Endoscopy showed a large ulcer in the stomach. Partial gastrectomy done and histopathology showed transmural infiltration by intermediate size atypical lymphoid cells which are immunopositive for CD3, CD56, TIA, EBV-encoded RNA (EBER) and negative for CD4, CD8, CD20. A diagnosis of extranodal NK/T cell lymphoma nasal type was made.https://journals.lww.com/10.4103/ijpm.ijpm_32_22extransal nk/t cell lymphomagastric perforationnk/t cell lymphoma
spellingShingle Prashant Mane
Prashant Ramteke
Anand Singh
Ajay Gogia
Saumyaranjan Mallick
Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature
Indian Journal of Pathology and Microbiology
extransal nk/t cell lymphoma
gastric perforation
nk/t cell lymphoma
title Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature
title_full Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature
title_fullStr Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature
title_full_unstemmed Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature
title_short Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature
title_sort primary extranodal nk t cell lymphoma of stomach a case report and review of literature
topic extransal nk/t cell lymphoma
gastric perforation
nk/t cell lymphoma
url https://journals.lww.com/10.4103/ijpm.ijpm_32_22
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