Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature
Extranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non-Hodgkin lymphoma and has a constant association with Epstein-Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero-digestive tract, of which stomach is a very rare site. Very few cases...
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Wolters Kluwer Medknow Publications
2024-04-01
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Series: | Indian Journal of Pathology and Microbiology |
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Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_32_22 |
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author | Prashant Mane Prashant Ramteke Anand Singh Ajay Gogia Saumyaranjan Mallick |
author_facet | Prashant Mane Prashant Ramteke Anand Singh Ajay Gogia Saumyaranjan Mallick |
author_sort | Prashant Mane |
collection | DOAJ |
description | Extranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non-Hodgkin lymphoma and has a constant association with Epstein-Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero-digestive tract, of which stomach is a very rare site. Very few cases of gastric extranodal NK/T cell lymphoma have been reported in the literature. A 22-year-old male patient presented with complaints of abdominal pain and hematemesis. Endoscopy showed a large ulcer in the stomach. Partial gastrectomy done and histopathology showed transmural infiltration by intermediate size atypical lymphoid cells which are immunopositive for CD3, CD56, TIA, EBV-encoded RNA (EBER) and negative for CD4, CD8, CD20. A diagnosis of extranodal NK/T cell lymphoma nasal type was made. |
format | Article |
id | doaj-art-0d983621bb6a4504b2edd67ccaad433a |
institution | Kabale University |
issn | 0377-4929 0974-5130 |
language | English |
publishDate | 2024-04-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Pathology and Microbiology |
spelling | doaj-art-0d983621bb6a4504b2edd67ccaad433a2025-02-07T14:01:49ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-04-01Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literaturePrashant ManePrashant RamtekeAnand SinghAjay GogiaSaumyaranjan MallickExtranodal Natural killer/T (NK/T) cell lymphoma nasal type is an aggressive non-Hodgkin lymphoma and has a constant association with Epstein-Barr virus (EBV) infection. Approximately more than 75% cases are located in upper aero-digestive tract, of which stomach is a very rare site. Very few cases of gastric extranodal NK/T cell lymphoma have been reported in the literature. A 22-year-old male patient presented with complaints of abdominal pain and hematemesis. Endoscopy showed a large ulcer in the stomach. Partial gastrectomy done and histopathology showed transmural infiltration by intermediate size atypical lymphoid cells which are immunopositive for CD3, CD56, TIA, EBV-encoded RNA (EBER) and negative for CD4, CD8, CD20. A diagnosis of extranodal NK/T cell lymphoma nasal type was made.https://journals.lww.com/10.4103/ijpm.ijpm_32_22extransal nk/t cell lymphomagastric perforationnk/t cell lymphoma |
spellingShingle | Prashant Mane Prashant Ramteke Anand Singh Ajay Gogia Saumyaranjan Mallick Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature Indian Journal of Pathology and Microbiology extransal nk/t cell lymphoma gastric perforation nk/t cell lymphoma |
title | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
title_full | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
title_fullStr | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
title_full_unstemmed | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
title_short | Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature |
title_sort | primary extranodal nk t cell lymphoma of stomach a case report and review of literature |
topic | extransal nk/t cell lymphoma gastric perforation nk/t cell lymphoma |
url | https://journals.lww.com/10.4103/ijpm.ijpm_32_22 |
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