Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry

Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry

IntroductionTaohong Siwu Decoction (THSW Decoction), a classic formula for treating blood stasis, has demonstrated significant clinical efficacy in the treatment of hepatic fibrosis. However, its primary active components and mechanisms of action remain unclear.MethodsIn this study, a carbon tetrach...

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Bibliographic Details
Main Authors: Shengsheng Li, Shenglan Qi, Rongsheng Li, Fangming Yang, Zhenyi Niu, Wei Liu, Suping Ma, Zhun Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
hepatic fibrosis
non-targeted metabolomics
molecular docking
Taohong Siwu decoction
mice
high resolution mass spectrometry
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1614341/full
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