The protective effects of propolis against lipopolysaccharide-induced acute liver injury by modulating serum metabolites and gut flora

Abstract Propolis has significant hepatoprotective effects, but the active components, targets, and mechanisms have not been fully elucidated. Here, we integrated network pharmacology, serum metabolomics, and 16 S rRNA sequencing to disclose the hepatoprotective effects of Chinese propolis (CP) by l...

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Bibliographic Details
Main Authors: Zhengxin Liu, Zongze Li, Yuyang Guo, Yajing Li, Hongzhuan Xuan
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-01343-1
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