Antileishmanial Activity of Aldonamides and N-Acyl-Diamine Derivatives

Antileishmanial Activity of Aldonamides and N-Acyl-Diamine Derivatives

A number of lipophilic N-acyl-diamines and aldonamides have been synthesized and tested for their in vitro antiproliferative activity against Leishmania amazonensis and L. chagasi. Ribonamides, having one amino group, displayed good to moderate inhibition of parasite growth. The best result was obta...

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Bibliographic Details
Main Authors: Elaine S. Coimbra, Camila G. Almeida, Wilson V. Júnior, Roberta C. N. Dos Reis, Ana C. F. De Almeida, Luana S. M. Forezi, Mauro V. De Almeida, Mireille Le Hyaric
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2008.100
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