Precision immune regulation in KRAS-mutated cancers: the final piece of the puzzle?

Precision immune regulation in KRAS-mutated cancers: the final piece of the puzzle?

Abstract In recent years, the development of targeted therapies for tumors with KRAS mutations has progressed rapidly, rendering the notion of KRAS as “undruggable” outdated. However, targeted therapies for KRAS mutations still face numerous challenges, including resistance, efficacy concerns, toxic...

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Bibliographic Details
Main Authors: Shenao Fu, Jiayao Ma, Changjing Cai, Jun Tan, Xiangying Deng, Hong Shen, Shan Zeng, Yihong Chen, Ying Han
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
KRAS
Cancer
Targeted therapy
Immunotherapy
Microenvironment
Online Access:https://doi.org/10.1186/s13046-025-03444-1
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