Clinical observation of an HIV-infected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor

The article describes the clinical observation of an HIVinfected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor, who is not receiving antiretroviral therapy. The follow-up showed the course of the disease over 20 years of follow-up, without receiving antiretroviral...

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Main Authors: Z. I. Akhmedjanova, D. M. Urunova, M. V. Zalyalieva
Format: Article
Language:Russian
Published: Journal Infectology 2021-07-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/1221
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author Z. I. Akhmedjanova
D. M. Urunova
M. V. Zalyalieva
author_facet Z. I. Akhmedjanova
D. M. Urunova
M. V. Zalyalieva
author_sort Z. I. Akhmedjanova
collection DOAJ
description The article describes the clinical observation of an HIVinfected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor, who is not receiving antiretroviral therapy. The follow-up showed the course of the disease over 20 years of follow-up, without receiving antiretroviral therapy, with a gradual decrease in the number of CD4-lymphocytes and an increase in viral load.
format Article
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institution Kabale University
issn 2072-6732
language Russian
publishDate 2021-07-01
publisher Journal Infectology
record_format Article
series Журнал инфектологии
spelling doaj-art-0d802d41af2b43aebeb9a14b6100132d2025-08-20T03:38:30ZrusJournal InfectologyЖурнал инфектологии2072-67322021-07-0113215916210.22625/2072-6732-2021-13-2-159-162923Clinical observation of an HIV-infected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptorZ. I. Akhmedjanova0D. M. Urunova1M. V. Zalyalieva2Institute of Immunology and GenomicsTashkent Institute for Advanced Training of PhysiciansInstitute of Immunology and GenomicsThe article describes the clinical observation of an HIVinfected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor, who is not receiving antiretroviral therapy. The follow-up showed the course of the disease over 20 years of follow-up, without receiving antiretroviral therapy, with a gradual decrease in the number of CD4-lymphocytes and an increase in viral load.https://journal.niidi.ru/jofin/article/view/1221hiv infectionantiretroviral therapycd4 lymphocytesviral loadlife expectancy
spellingShingle Z. I. Akhmedjanova
D. M. Urunova
M. V. Zalyalieva
Clinical observation of an HIV-infected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor
Журнал инфектологии
hiv infection
antiretroviral therapy
cd4 lymphocytes
viral load
life expectancy
title Clinical observation of an HIV-infected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor
title_full Clinical observation of an HIV-infected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor
title_fullStr Clinical observation of an HIV-infected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor
title_full_unstemmed Clinical observation of an HIV-infected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor
title_short Clinical observation of an HIV-infected patient heterozygous for the mutant allele of the CCR5 del 32 chemokine receptor
title_sort clinical observation of an hiv infected patient heterozygous for the mutant allele of the ccr5 del 32 chemokine receptor
topic hiv infection
antiretroviral therapy
cd4 lymphocytes
viral load
life expectancy
url https://journal.niidi.ru/jofin/article/view/1221
work_keys_str_mv AT ziakhmedjanova clinicalobservationofanhivinfectedpatientheterozygousforthemutantalleleoftheccr5del32chemokinereceptor
AT dmurunova clinicalobservationofanhivinfectedpatientheterozygousforthemutantalleleoftheccr5del32chemokinereceptor
AT mvzalyalieva clinicalobservationofanhivinfectedpatientheterozygousforthemutantalleleoftheccr5del32chemokinereceptor