Research progress of Chinese medicinal monomers in the process of melanoma occurrence
Context Melanoma’s aggressiveness and resistance to radiotherapy highlight an urgent need for innovative treatments. Traditional Chinese medicine (TCM) offers a unique approach through its ‘four natures’ theory—cold, cool, warm, and hot.Objective This review aims to explore the potential of TCM’s ‘f...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Pharmaceutical Biology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/13880209.2024.2445695 |
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| author | Yan Shang Hailong Zhao |
| author_facet | Yan Shang Hailong Zhao |
| author_sort | Yan Shang |
| collection | DOAJ |
| description | Context Melanoma’s aggressiveness and resistance to radiotherapy highlight an urgent need for innovative treatments. Traditional Chinese medicine (TCM) offers a unique approach through its ‘four natures’ theory—cold, cool, warm, and hot.Objective This review aims to explore the potential of TCM’s ‘four natures’ herbal monomers in melanoma treatment, providing an alternative to conventional therapies.Materials & methods A systematic literature review was conducted by accessing various databases, including Baidu Scholar, PubMed, Science Citation Index Expanded (SCIE), and China National Knowledge Infrastructure (CNKI), to synthesize the most recent findings on traditional Chinese medicine monomers. Furthermore, this review elucidated the mechanisms underlying their role in melanoma retention.Results TCM’s multi-component, multi-target approach has shown promise in addressing melanoma’s complexity, with specific monomers demonstrating the ability to modulate tumor behavior.Discussion and Conclusions The ‘four natures’ theory in TCM presents a novel perspective for melanoma treatment, warranting further investigation into its clinical applications and potential integration with modern oncology. |
| format | Article |
| id | doaj-art-0d7f2cec2b4b40e6ab019df784e4fc2b |
| institution | OA Journals |
| issn | 1388-0209 1744-5116 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Pharmaceutical Biology |
| spelling | doaj-art-0d7f2cec2b4b40e6ab019df784e4fc2b2025-08-20T02:36:15ZengTaylor & Francis GroupPharmaceutical Biology1388-02091744-51162025-12-01631536710.1080/13880209.2024.2445695Research progress of Chinese medicinal monomers in the process of melanoma occurrenceYan Shang0Hailong Zhao1Department of Pathophysiology, Zunyi Medical University, Zunyi, ChinaDepartment of Pathophysiology, Zunyi Medical University, Zunyi, ChinaContext Melanoma’s aggressiveness and resistance to radiotherapy highlight an urgent need for innovative treatments. Traditional Chinese medicine (TCM) offers a unique approach through its ‘four natures’ theory—cold, cool, warm, and hot.Objective This review aims to explore the potential of TCM’s ‘four natures’ herbal monomers in melanoma treatment, providing an alternative to conventional therapies.Materials & methods A systematic literature review was conducted by accessing various databases, including Baidu Scholar, PubMed, Science Citation Index Expanded (SCIE), and China National Knowledge Infrastructure (CNKI), to synthesize the most recent findings on traditional Chinese medicine monomers. Furthermore, this review elucidated the mechanisms underlying their role in melanoma retention.Results TCM’s multi-component, multi-target approach has shown promise in addressing melanoma’s complexity, with specific monomers demonstrating the ability to modulate tumor behavior.Discussion and Conclusions The ‘four natures’ theory in TCM presents a novel perspective for melanoma treatment, warranting further investigation into its clinical applications and potential integration with modern oncology.https://www.tandfonline.com/doi/10.1080/13880209.2024.2445695MelanomaChinese medicinal monomersherbal antitumor activitytraditional Chinese medication (TCM)melanomagenesis inhibition |
| spellingShingle | Yan Shang Hailong Zhao Research progress of Chinese medicinal monomers in the process of melanoma occurrence Pharmaceutical Biology Melanoma Chinese medicinal monomers herbal antitumor activity traditional Chinese medication (TCM) melanomagenesis inhibition |
| title | Research progress of Chinese medicinal monomers in the process of melanoma occurrence |
| title_full | Research progress of Chinese medicinal monomers in the process of melanoma occurrence |
| title_fullStr | Research progress of Chinese medicinal monomers in the process of melanoma occurrence |
| title_full_unstemmed | Research progress of Chinese medicinal monomers in the process of melanoma occurrence |
| title_short | Research progress of Chinese medicinal monomers in the process of melanoma occurrence |
| title_sort | research progress of chinese medicinal monomers in the process of melanoma occurrence |
| topic | Melanoma Chinese medicinal monomers herbal antitumor activity traditional Chinese medication (TCM) melanomagenesis inhibition |
| url | https://www.tandfonline.com/doi/10.1080/13880209.2024.2445695 |
| work_keys_str_mv | AT yanshang researchprogressofchinesemedicinalmonomersintheprocessofmelanomaoccurrence AT hailongzhao researchprogressofchinesemedicinalmonomersintheprocessofmelanomaoccurrence |