BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1
Abstract. Defensin amounts in severe forms of influenza-associated pneumonia and acute respiratory distresssyndrome is increased to a lesser degree than in pneumonias with milder clinical course. This difference may be determined by selective accumulation of defensins in areas of infectious lesions....
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
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| Online Access: | https://www.mimmun.ru/mimmun/article/view/361 |
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| _version_ | 1849241457355915264 |
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| author | E. N. Romanova A. V. Govorin V. V. Gorbunov S. A. Lukyanov |
| author_facet | E. N. Romanova A. V. Govorin V. V. Gorbunov S. A. Lukyanov |
| author_sort | E. N. Romanova |
| collection | DOAJ |
| description | Abstract. Defensin amounts in severe forms of influenza-associated pneumonia and acute respiratory distresssyndrome is increased to a lesser degree than in pneumonias with milder clinical course. This difference may be determined by selective accumulation of defensins in areas of infectious lesions. Mean content of α-defensins in non-severe pneumonias with influenza А/H1N1 accompanied by normocytosis or leukopenia, is higher than in bacterial pneumonias with leukocytosis. High levels of defensins, along with substantially increased neutrophil counts, associated with normocytosis or leukopenia, reflect a pronounced systemic inflammatory response caused by influenza А/H1N1. |
| format | Article |
| id | doaj-art-0d7b510312dc42d3be5de357e499bb6e |
| institution | Kabale University |
| issn | 1563-0625 2313-741X |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj-art-0d7b510312dc42d3be5de357e499bb6e2025-08-20T04:00:09ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0114323924210.15789/1563-0625-2012-3-239-242358BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1E. N. Romanova0A. V. Govorin1V. V. Gorbunov2S. A. Lukyanov3ГБОУ ВПО «Читинская государственная медицинская академия» Минздравсоцразвития России, г. ЧитаГБОУ ВПО «Читинская государственная медицинская академия» Минздравсоцразвития России, г. ЧитаГБОУ ВПО «Читинская государственная медицинская академия» Минздравсоцразвития России, г. ЧитаГБОУ ВПО «Читинская государственная медицинская академия» Минздравсоцразвития России, г. ЧитаAbstract. Defensin amounts in severe forms of influenza-associated pneumonia and acute respiratory distresssyndrome is increased to a lesser degree than in pneumonias with milder clinical course. This difference may be determined by selective accumulation of defensins in areas of infectious lesions. Mean content of α-defensins in non-severe pneumonias with influenza А/H1N1 accompanied by normocytosis or leukopenia, is higher than in bacterial pneumonias with leukocytosis. High levels of defensins, along with substantially increased neutrophil counts, associated with normocytosis or leukopenia, reflect a pronounced systemic inflammatory response caused by influenza А/H1N1.https://www.mimmun.ru/mimmun/article/view/361influenza a/h1n1defensinspneumoniaacute respiratory distress-syndrome |
| spellingShingle | E. N. Romanova A. V. Govorin V. V. Gorbunov S. A. Lukyanov BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1 Медицинская иммунология influenza a/h1n1 defensins pneumonia acute respiratory distress-syndrome |
| title | BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1 |
| title_full | BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1 |
| title_fullStr | BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1 |
| title_full_unstemmed | BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1 |
| title_short | BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1 |
| title_sort | blood contents of defensins in patients with pneumonias caused by influenza а h1n1 |
| topic | influenza a/h1n1 defensins pneumonia acute respiratory distress-syndrome |
| url | https://www.mimmun.ru/mimmun/article/view/361 |
| work_keys_str_mv | AT enromanova bloodcontentsofdefensinsinpatientswithpneumoniascausedbyinfluenzaah1n1 AT avgovorin bloodcontentsofdefensinsinpatientswithpneumoniascausedbyinfluenzaah1n1 AT vvgorbunov bloodcontentsofdefensinsinpatientswithpneumoniascausedbyinfluenzaah1n1 AT salukyanov bloodcontentsofdefensinsinpatientswithpneumoniascausedbyinfluenzaah1n1 |