Central Hemodynamics and Microcirculation in Critical Conditions
Objective: to compare central hemodynamic and microcirculatory changes in critical conditions caused by different factors and to reveal their possible differences for a further differentiated approach to intensive therapy. Subjects and methods. The study covered 16 subjects with severe concomitant i...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2013-02-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/162 |
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| author | A. A. Kosovskikh Yu. A. Churlyaev S. L. Kan A. N. Lyzlov T. V. Kirsanov A. R. Vartanyan |
| author_facet | A. A. Kosovskikh Yu. A. Churlyaev S. L. Kan A. N. Lyzlov T. V. Kirsanov A. R. Vartanyan |
| author_sort | A. A. Kosovskikh |
| collection | DOAJ |
| description | Objective: to compare central hemodynamic and microcirculatory changes in critical conditions caused by different factors and to reveal their possible differences for a further differentiated approach to intensive therapy. Subjects and methods. The study covered 16 subjects with severe concomitant injury (mean age 41.96±2.83 years) and 19 patients with general purulent peritonitis (mean age 45.34±2.16 years). Their follow-up was 7 days. The central hemodynamics was estimated by transpulmonary thermodilution using a Pulsion PiCCO Plus system (Pulsion Medical Systems, Germany). The microcirculatory bed was evaluated by cutaneous laser Doppler flowmetry using a LAKK-02 capillary blood flow laser analyzer (LAZMA Research-and-Production Association, Russian Federation). Results. The pattern of central hemodynamic and microcirculatory disorders varies with the trigger that has led to a critical condition. Central hemodynamics should be stabilized to ensure the average level of tissue perfusion in victims with severe concomitant injury. In general purulent peritonitis, microcirculatory disorders may persist even if the macrohemodynamic parameters are normal. Conclusion. The macrohemodynamic and microcirculatory differences obtained during the study suggest that a complex of intensive therapy should be differentiated and, if the latter is used, it is necessary not only to be based on the central hemodynamics, but also to take into consideration functional changes in microcirculation. Key words: severe concomitant injury, general purulent peritonitis, micro-circulation, central hemodynamics, type of circulation. |
| format | Article |
| id | doaj-art-0d77a33bfb8b4bc5926374ec4cf6dc6a |
| institution | Kabale University |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2013-02-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-0d77a33bfb8b4bc5926374ec4cf6dc6a2025-08-20T03:35:08ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102013-02-019110.15360/1813-9779-2013-1-18162Central Hemodynamics and Microcirculation in Critical ConditionsA. A. KosovskikhYu. A. ChurlyaevS. L. KanA. N. LyzlovT. V. KirsanovA. R. VartanyanObjective: to compare central hemodynamic and microcirculatory changes in critical conditions caused by different factors and to reveal their possible differences for a further differentiated approach to intensive therapy. Subjects and methods. The study covered 16 subjects with severe concomitant injury (mean age 41.96±2.83 years) and 19 patients with general purulent peritonitis (mean age 45.34±2.16 years). Their follow-up was 7 days. The central hemodynamics was estimated by transpulmonary thermodilution using a Pulsion PiCCO Plus system (Pulsion Medical Systems, Germany). The microcirculatory bed was evaluated by cutaneous laser Doppler flowmetry using a LAKK-02 capillary blood flow laser analyzer (LAZMA Research-and-Production Association, Russian Federation). Results. The pattern of central hemodynamic and microcirculatory disorders varies with the trigger that has led to a critical condition. Central hemodynamics should be stabilized to ensure the average level of tissue perfusion in victims with severe concomitant injury. In general purulent peritonitis, microcirculatory disorders may persist even if the macrohemodynamic parameters are normal. Conclusion. The macrohemodynamic and microcirculatory differences obtained during the study suggest that a complex of intensive therapy should be differentiated and, if the latter is used, it is necessary not only to be based on the central hemodynamics, but also to take into consideration functional changes in microcirculation. Key words: severe concomitant injury, general purulent peritonitis, micro-circulation, central hemodynamics, type of circulation.https://www.reanimatology.com/rmt/article/view/162 |
| spellingShingle | A. A. Kosovskikh Yu. A. Churlyaev S. L. Kan A. N. Lyzlov T. V. Kirsanov A. R. Vartanyan Central Hemodynamics and Microcirculation in Critical Conditions Общая реаниматология |
| title | Central Hemodynamics and Microcirculation in Critical Conditions |
| title_full | Central Hemodynamics and Microcirculation in Critical Conditions |
| title_fullStr | Central Hemodynamics and Microcirculation in Critical Conditions |
| title_full_unstemmed | Central Hemodynamics and Microcirculation in Critical Conditions |
| title_short | Central Hemodynamics and Microcirculation in Critical Conditions |
| title_sort | central hemodynamics and microcirculation in critical conditions |
| url | https://www.reanimatology.com/rmt/article/view/162 |
| work_keys_str_mv | AT aakosovskikh centralhemodynamicsandmicrocirculationincriticalconditions AT yuachurlyaev centralhemodynamicsandmicrocirculationincriticalconditions AT slkan centralhemodynamicsandmicrocirculationincriticalconditions AT anlyzlov centralhemodynamicsandmicrocirculationincriticalconditions AT tvkirsanov centralhemodynamicsandmicrocirculationincriticalconditions AT arvartanyan centralhemodynamicsandmicrocirculationincriticalconditions |