Bereitschaftspotential preceding eyelid blinks in Parkinson’s disease
ABSTRACT The Bereitschaftspotential (BP) is a negative wave observed in EEG retrograde averaging, preceding a motor act. The objective was to study the BP preceding voluntary eyelid blinks in Parkinson’s disease (PD) patients during off and on phases of levodopa. Methods Ten PD patients in stages...
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000800539&lng=en&tlng=en |
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| author | Isabella Araújo Mota Maria das Graças Coriolano Otávio Gomes Lins |
| author_facet | Isabella Araújo Mota Maria das Graças Coriolano Otávio Gomes Lins |
| author_sort | Isabella Araújo Mota |
| collection | DOAJ |
| description | ABSTRACT The Bereitschaftspotential (BP) is a negative wave observed in EEG retrograde averaging, preceding a motor act. The objective was to study the BP preceding voluntary eyelid blinks in Parkinson’s disease (PD) patients during off and on phases of levodopa. Methods Ten PD patients in stages 1 and 2 of the Hoehn & Yahr classification were compared to 18 healthy controls. Artifact-free EEG segments of two seconds preceding the onset of the blink potential were averaged and analyzed, and the statistical significance of the measured amplitudes were evaluated by analysis of variance models. Results The presence of a BP in the PD patients was demonstrated. The mean amplitudes at 0 ms were respectively 0.6 µV and 3.3 µV for the BP patients and the normal controls, respectively. Conclusions The BP amplitudes were significantly smaller in PD patients than normal participants. The amplitudes of the BP were not modified by levodopa. |
| format | Article |
| id | doaj-art-0d776eef46e84d37a8725aabbcb2bc97 |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-0d776eef46e84d37a8725aabbcb2bc972025-08-20T01:59:27ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-422775853954510.1590/0004-282x20170109S0004-282X2017000800539Bereitschaftspotential preceding eyelid blinks in Parkinson’s diseaseIsabella Araújo MotaMaria das Graças CoriolanoOtávio Gomes LinsABSTRACT The Bereitschaftspotential (BP) is a negative wave observed in EEG retrograde averaging, preceding a motor act. The objective was to study the BP preceding voluntary eyelid blinks in Parkinson’s disease (PD) patients during off and on phases of levodopa. Methods Ten PD patients in stages 1 and 2 of the Hoehn & Yahr classification were compared to 18 healthy controls. Artifact-free EEG segments of two seconds preceding the onset of the blink potential were averaged and analyzed, and the statistical significance of the measured amplitudes were evaluated by analysis of variance models. Results The presence of a BP in the PD patients was demonstrated. The mean amplitudes at 0 ms were respectively 0.6 µV and 3.3 µV for the BP patients and the normal controls, respectively. Conclusions The BP amplitudes were significantly smaller in PD patients than normal participants. The amplitudes of the BP were not modified by levodopa.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000800539&lng=en&tlng=encontingent negative variationParkinson diseaselevodopa |
| spellingShingle | Isabella Araújo Mota Maria das Graças Coriolano Otávio Gomes Lins Bereitschaftspotential preceding eyelid blinks in Parkinson’s disease Arquivos de Neuro-Psiquiatria contingent negative variation Parkinson disease levodopa |
| title | Bereitschaftspotential preceding eyelid blinks in Parkinson’s disease |
| title_full | Bereitschaftspotential preceding eyelid blinks in Parkinson’s disease |
| title_fullStr | Bereitschaftspotential preceding eyelid blinks in Parkinson’s disease |
| title_full_unstemmed | Bereitschaftspotential preceding eyelid blinks in Parkinson’s disease |
| title_short | Bereitschaftspotential preceding eyelid blinks in Parkinson’s disease |
| title_sort | bereitschaftspotential preceding eyelid blinks in parkinson s disease |
| topic | contingent negative variation Parkinson disease levodopa |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000800539&lng=en&tlng=en |
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