Artificial saliva effect on toxic substances release from acrylic resins

Background/Aim. Acrylic-based resins are intensively used in dentistry practice as restorative or denture-base materials. The purpose of this study was to analyze the surface structure of denture base resins and the amount of released potentially toxic substances (PTS) immediately upon p...

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Main Authors: Kostić Milena, Krunić Nebojša, Najman Stevo, Nikolić Ljubiša, Nikolić Vesna, Rajković Jelena, Petrović Milica, Igić Marko, Ignjatović Aleksandra
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2015-01-01
Series:Vojnosanitetski Pregled
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Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500070K.pdf
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author Kostić Milena
Krunić Nebojša
Najman Stevo
Nikolić Ljubiša
Nikolić Vesna
Rajković Jelena
Petrović Milica
Igić Marko
Ignjatović Aleksandra
author_facet Kostić Milena
Krunić Nebojša
Najman Stevo
Nikolić Ljubiša
Nikolić Vesna
Rajković Jelena
Petrović Milica
Igić Marko
Ignjatović Aleksandra
author_sort Kostić Milena
collection DOAJ
description Background/Aim. Acrylic-based resins are intensively used in dentistry practice as restorative or denture-base materials. The purpose of this study was to analyze the surface structure of denture base resins and the amount of released potentially toxic substances (PTS) immediately upon polymerization and incubation in different types of artificial saliva. Methods. Storage of acrylic samples in two models of artificial saliva were performed in a water bath at the temperature of 37 ± 1°C. Analysis of the surface structure of samples was carried out using scanning electronic microscopy analysis immediately after polymerization and after the 30-day incubation. The amounts of PTS per day, week and month extracts were measured using high-pressure liquid chromatography. Results. Surface design and amount of PTS in acrylic materials were different and depended on the types and duration of polymerization. The surfaces of tested acrylates became flatter after immersing in solutions of artificial saliva. The degree of acrylic materials release was not dependent on the applied model of artificial saliva. Conclusion. In order to improve biological features of acrylic resin materials, it was recommended that dentures lined with soft or hard coldpolymerized acrylates should be kept at least 1 to 7 days in water before being given to a patient. So, as to reach high degree of biocompatibility preparation of prosthetic restorations from heat-polymerized acrylate was unnecessary. [Projekat Ministarstva nauke Republike Srbije, br. 41017]
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language English
publishDate 2015-01-01
publisher Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
record_format Article
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spelling doaj-art-0d6c940e9b664ef79d6bb6d64124756d2025-08-20T03:17:02ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202015-01-01721089990510.2298/VSP140304070K0042-84501500070KArtificial saliva effect on toxic substances release from acrylic resinsKostić Milena0Krunić Nebojša1Najman Stevo2Nikolić Ljubiša3Nikolić Vesna4Rajković Jelena5Petrović Milica6Igić Marko7Ignjatović Aleksandra8University of Niš, Faculty of Medicine, Clinic of Dentistry, Department of Prosthetic Dentistry, Niš, SerbiaUniversity of Niš, Faculty of Medicine, Clinic of Dentistry, Department of Prosthetic Dentistry, Niš, SerbiaUniversity of Niš, Faculty of Medicine, Institute of Biology and Human Genetics, Niš, SerbiaUniversity of Niš, Faculty of Technology, Leskovac, SerbiaUniversity of Niš, Faculty of Technology, Leskovac, SerbiaUniversity of Niš, Faculty of Sciences and Mathematics, Niš, SerbiaUniversity of Niš, Faculty of Medicine, Clinic of Dentistry, Department of Prosthetic Dentistry, Niš, SerbiaUniversity of Niš, Faculty of Medicine, Clinic of Dentistry, Department of Prosthetic Dentistry, Niš, SerbiaUniversity of Niš, Faculty of Medicine, Department of Medical Statistics, Niš, SerbiaBackground/Aim. Acrylic-based resins are intensively used in dentistry practice as restorative or denture-base materials. The purpose of this study was to analyze the surface structure of denture base resins and the amount of released potentially toxic substances (PTS) immediately upon polymerization and incubation in different types of artificial saliva. Methods. Storage of acrylic samples in two models of artificial saliva were performed in a water bath at the temperature of 37 ± 1°C. Analysis of the surface structure of samples was carried out using scanning electronic microscopy analysis immediately after polymerization and after the 30-day incubation. The amounts of PTS per day, week and month extracts were measured using high-pressure liquid chromatography. Results. Surface design and amount of PTS in acrylic materials were different and depended on the types and duration of polymerization. The surfaces of tested acrylates became flatter after immersing in solutions of artificial saliva. The degree of acrylic materials release was not dependent on the applied model of artificial saliva. Conclusion. In order to improve biological features of acrylic resin materials, it was recommended that dentures lined with soft or hard coldpolymerized acrylates should be kept at least 1 to 7 days in water before being given to a patient. So, as to reach high degree of biocompatibility preparation of prosthetic restorations from heat-polymerized acrylate was unnecessary. [Projekat Ministarstva nauke Republike Srbije, br. 41017]http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500070K.pdfacrylic resinssalivaartificialhazardous substances
spellingShingle Kostić Milena
Krunić Nebojša
Najman Stevo
Nikolić Ljubiša
Nikolić Vesna
Rajković Jelena
Petrović Milica
Igić Marko
Ignjatović Aleksandra
Artificial saliva effect on toxic substances release from acrylic resins
Vojnosanitetski Pregled
acrylic resins
saliva
artificial
hazardous substances
title Artificial saliva effect on toxic substances release from acrylic resins
title_full Artificial saliva effect on toxic substances release from acrylic resins
title_fullStr Artificial saliva effect on toxic substances release from acrylic resins
title_full_unstemmed Artificial saliva effect on toxic substances release from acrylic resins
title_short Artificial saliva effect on toxic substances release from acrylic resins
title_sort artificial saliva effect on toxic substances release from acrylic resins
topic acrylic resins
saliva
artificial
hazardous substances
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500070K.pdf
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AT nikolicljubisa artificialsalivaeffectontoxicsubstancesreleasefromacrylicresins
AT nikolicvesna artificialsalivaeffectontoxicsubstancesreleasefromacrylicresins
AT rajkovicjelena artificialsalivaeffectontoxicsubstancesreleasefromacrylicresins
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