An adaptive deep learning approach based on InBNFus and CNNDen-GRU networks for breast cancer and maternal fetal classification using ultrasound images

Abstract Convolutional Neural Networks (CNNs), a sophisticated deep learning technique, have proven highly effective in identifying and classifying abnormalities related to various diseases. The manual classification of these is a hectic and time-consuming process; therefore, it is essential to deve...

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Main Authors: Mamuna Fatima, Muhammad Attique Khan, Anwar M. Mirza, Jungpil Shin, Areej Alasiry, Mehrez Marzougui, Jaehyuk Cha, Byoungchol Chang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-03402-z
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author Mamuna Fatima
Muhammad Attique Khan
Anwar M. Mirza
Jungpil Shin
Areej Alasiry
Mehrez Marzougui
Jaehyuk Cha
Byoungchol Chang
author_facet Mamuna Fatima
Muhammad Attique Khan
Anwar M. Mirza
Jungpil Shin
Areej Alasiry
Mehrez Marzougui
Jaehyuk Cha
Byoungchol Chang
author_sort Mamuna Fatima
collection DOAJ
description Abstract Convolutional Neural Networks (CNNs), a sophisticated deep learning technique, have proven highly effective in identifying and classifying abnormalities related to various diseases. The manual classification of these is a hectic and time-consuming process; therefore, it is essential to develop a computerized technique. Most existing methods are designed to address a single specific problem, limiting their adaptability. In this work, we proposed a novel adaptive deep-learning framework for simultaneously classifying breast cancer and maternal-fetal ultrasound datasets. Data augmentation was applied in the preprocessing phase to address the data imbalance problem. After, two novel architectures are proposed: InBnFUS and CNNDen-GRU. The InBnFUS network combines 5-Blocks inception-based architecture (Model 1) and 5-Blocks inverted bottleneck-based architecture (Model 2) through a depth-wise concatenation layer, while CNNDen-GRU incorporates 5-Blocks dense architecture with an integrated GRU layer. Post-training features were extracted from the global average pooling and GRU layer and classified using neural network classifiers. The experimental evaluation achieved enhanced accuracy rates of 99.0% for breast cancer, 96.6% for maternal-fetal (common planes), and 94.6% for maternal-fetal (brain) datasets. Additionally, the models consistently achieve high precision, recall, and F1 scores across both datasets. A comprehensive ablation study has been performed, and the results show the superior performance of the proposed models.
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spelling doaj-art-0d69fb3820cb4c2b93d6ad50caef35922025-08-20T03:45:28ZengNature PortfolioScientific Reports2045-23222025-07-0115111810.1038/s41598-025-03402-zAn adaptive deep learning approach based on InBNFus and CNNDen-GRU networks for breast cancer and maternal fetal classification using ultrasound imagesMamuna Fatima0Muhammad Attique Khan1Anwar M. Mirza2Jungpil Shin3Areej Alasiry4Mehrez Marzougui5Jaehyuk Cha6Byoungchol Chang7Department of Computer Science, COMSATS University IslamabadDepartment of AI, College of Computer Engineering and Science, Prince Mohammad Bin Fahd UniversityDepartment of AI, College of Computer Engineering and Science, Prince Mohammad Bin Fahd UniversitySchool of Computer Science and Engineering, The University of AizuCollege of Computer Science, King Khalid UniversityCollege of Computer Science, King Khalid UniversityHanynag UniversityHanynag UniversityAbstract Convolutional Neural Networks (CNNs), a sophisticated deep learning technique, have proven highly effective in identifying and classifying abnormalities related to various diseases. The manual classification of these is a hectic and time-consuming process; therefore, it is essential to develop a computerized technique. Most existing methods are designed to address a single specific problem, limiting their adaptability. In this work, we proposed a novel adaptive deep-learning framework for simultaneously classifying breast cancer and maternal-fetal ultrasound datasets. Data augmentation was applied in the preprocessing phase to address the data imbalance problem. After, two novel architectures are proposed: InBnFUS and CNNDen-GRU. The InBnFUS network combines 5-Blocks inception-based architecture (Model 1) and 5-Blocks inverted bottleneck-based architecture (Model 2) through a depth-wise concatenation layer, while CNNDen-GRU incorporates 5-Blocks dense architecture with an integrated GRU layer. Post-training features were extracted from the global average pooling and GRU layer and classified using neural network classifiers. The experimental evaluation achieved enhanced accuracy rates of 99.0% for breast cancer, 96.6% for maternal-fetal (common planes), and 94.6% for maternal-fetal (brain) datasets. Additionally, the models consistently achieve high precision, recall, and F1 scores across both datasets. A comprehensive ablation study has been performed, and the results show the superior performance of the proposed models.https://doi.org/10.1038/s41598-025-03402-zBreast cancerSparse autoencodersData augmentationImage processingFusionClassification
spellingShingle Mamuna Fatima
Muhammad Attique Khan
Anwar M. Mirza
Jungpil Shin
Areej Alasiry
Mehrez Marzougui
Jaehyuk Cha
Byoungchol Chang
An adaptive deep learning approach based on InBNFus and CNNDen-GRU networks for breast cancer and maternal fetal classification using ultrasound images
Scientific Reports
Breast cancer
Sparse autoencoders
Data augmentation
Image processing
Fusion
Classification
title An adaptive deep learning approach based on InBNFus and CNNDen-GRU networks for breast cancer and maternal fetal classification using ultrasound images
title_full An adaptive deep learning approach based on InBNFus and CNNDen-GRU networks for breast cancer and maternal fetal classification using ultrasound images
title_fullStr An adaptive deep learning approach based on InBNFus and CNNDen-GRU networks for breast cancer and maternal fetal classification using ultrasound images
title_full_unstemmed An adaptive deep learning approach based on InBNFus and CNNDen-GRU networks for breast cancer and maternal fetal classification using ultrasound images
title_short An adaptive deep learning approach based on InBNFus and CNNDen-GRU networks for breast cancer and maternal fetal classification using ultrasound images
title_sort adaptive deep learning approach based on inbnfus and cnnden gru networks for breast cancer and maternal fetal classification using ultrasound images
topic Breast cancer
Sparse autoencoders
Data augmentation
Image processing
Fusion
Classification
url https://doi.org/10.1038/s41598-025-03402-z
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