Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review
The clinical presentation of primary hyperparathyroidism (PHPT) has evolved over the years from a symptomatic disorder to a predominantly asymptomatic condition. Altered vitamin D metabolism seems to play a role in the presentation of PHPT and may exacerbate the severity of disease. The epidemiology...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2023/1169249 |
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| _version_ | 1849308701932912640 |
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| author | Niharika Yedla Hyon Kim Anupa Sharma Xiangbing Wang |
| author_facet | Niharika Yedla Hyon Kim Anupa Sharma Xiangbing Wang |
| author_sort | Niharika Yedla |
| collection | DOAJ |
| description | The clinical presentation of primary hyperparathyroidism (PHPT) has evolved over the years from a symptomatic disorder to a predominantly asymptomatic condition. Altered vitamin D metabolism seems to play a role in the presentation of PHPT and may exacerbate the severity of disease. The epidemiology of PHPT differs in the developing versus the developed world, where more severe phenotypes occur in regions where vitamin D deficiency is common. Although it has been validated that patients with PHPT should be vitamin D sufficient, the threshold to supplement in relation to the severity of PHPT and the degree of vitamin D deficiency remains controversial. This review will highlight some of the controversy regarding vitamin D deficiency and the different phenotypes of PHPT. |
| format | Article |
| id | doaj-art-0d68723c3d9c408cb2e4697c2234af30 |
| institution | Kabale University |
| issn | 1687-8345 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-0d68723c3d9c408cb2e4697c2234af302025-08-20T03:54:24ZengWileyInternational Journal of Endocrinology1687-83452023-01-01202310.1155/2023/1169249Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini ReviewNiharika Yedla0Hyon Kim1Anupa Sharma2Xiangbing Wang3Department of EndocrinologyDivision of EndocrinologyPenn Medicine Princeton Medicine PhysiciansDivision of EndocrinologyThe clinical presentation of primary hyperparathyroidism (PHPT) has evolved over the years from a symptomatic disorder to a predominantly asymptomatic condition. Altered vitamin D metabolism seems to play a role in the presentation of PHPT and may exacerbate the severity of disease. The epidemiology of PHPT differs in the developing versus the developed world, where more severe phenotypes occur in regions where vitamin D deficiency is common. Although it has been validated that patients with PHPT should be vitamin D sufficient, the threshold to supplement in relation to the severity of PHPT and the degree of vitamin D deficiency remains controversial. This review will highlight some of the controversy regarding vitamin D deficiency and the different phenotypes of PHPT.http://dx.doi.org/10.1155/2023/1169249 |
| spellingShingle | Niharika Yedla Hyon Kim Anupa Sharma Xiangbing Wang Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review International Journal of Endocrinology |
| title | Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review |
| title_full | Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review |
| title_fullStr | Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review |
| title_full_unstemmed | Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review |
| title_short | Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review |
| title_sort | vitamin d deficiency and the presentation of primary hyperparathyroidism a mini review |
| url | http://dx.doi.org/10.1155/2023/1169249 |
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