Extending Investigations of miR‐126‐5p on the Regulation of CYP2A6, the Major Nicotine‐Inactivating Enzyme
ABSTRACT CYP2A6 is the hepatic enzyme responsible for the metabolic inactivation of nicotine. Variation in CYP2A6 alters nicotine clearance, affecting numerous smoking behaviors and tobacco‐related diseases, making investigating sources of variation important. A published molecular study of microRNA...
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| Main Authors: | Weilong Gu, Alec W. R. Langlois, Haidy Giratallah, Katrina G. Claw, Bhagwat Prasad, Kenneth E. Thummel, Rachel F. Tyndale |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-08-01
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| Series: | Pharmacology Research & Perspectives |
| Online Access: | https://doi.org/10.1002/prp2.70149 |
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