Symptom clusters and resting cardiovascular autonomic measures in adolescents: From acute concussion to recovery
Abstract Sport‐related concussion (SRC) is associated with cardiovascular autonomic nervous system (ANS) dysfunction. This study examines resting cardiovascular ANS activity in adolescents with SRC compared to controls early post‐injury and after clinical recovery, analyzing its correlation with sym...
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| Format: | Article |
| Language: | English |
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Wiley
2024-11-01
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| Series: | Physiological Reports |
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| Online Access: | https://doi.org/10.14814/phy2.70114 |
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| author | Wenjie Ji Haley M. Chizuk John J. Leddy Sue A. Sisto Mohammad N. Haider |
| author_facet | Wenjie Ji Haley M. Chizuk John J. Leddy Sue A. Sisto Mohammad N. Haider |
| author_sort | Wenjie Ji |
| collection | DOAJ |
| description | Abstract Sport‐related concussion (SRC) is associated with cardiovascular autonomic nervous system (ANS) dysfunction. This study examines resting cardiovascular ANS activity in adolescents with SRC compared to controls early post‐injury and after clinical recovery, analyzing its correlation with symptom severity and recovery outcomes. Cardiovascular ANS function was evaluated using heart rate variability (HRV), systolic blood pressure variability (SBPV) and baroreflex sensitivity (BRS). Symptoms were assessed via the Post‐Concussion Symptom Scale, and recovery outcomes were categorized by recovery duration. Following acute SRC, no significant differences in HRV, SBPV or BRS were found between SRC and control groups, nor between those with delayed or normal recovery. Post‐recovery, SRC participants had higher low frequency (LF) SBPV than controls and their initial assessment. When concussed participants were symptomatic, LF SBPV correlated directly with overall, cognitive, and fatigue symptom severity, while high frequency (HF) HRV inversely correlated with affective symptoms (Spearman's rho: 0.4–0.6). Resting cardiovascular ANS function remains unchanged in adolescent athletes acutely after SRC, suggesting it has limited diagnostic and prognostic potential. Although some correlations between individual symptom domains and ANS activity were observed, they were not significantly different from asymptomatic controls, limiting the ability to interpret these findings. |
| format | Article |
| id | doaj-art-0d582da329344d7bb922463ee708aaa2 |
| institution | Kabale University |
| issn | 2051-817X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Physiological Reports |
| spelling | doaj-art-0d582da329344d7bb922463ee708aaa22025-01-25T06:41:00ZengWileyPhysiological Reports2051-817X2024-11-011221n/an/a10.14814/phy2.70114Symptom clusters and resting cardiovascular autonomic measures in adolescents: From acute concussion to recoveryWenjie Ji0Haley M. Chizuk1John J. Leddy2Sue A. Sisto3Mohammad N. Haider4Department of Rehabilitation Science School of Public Health and Health Professions, State University of New York at Buffalo Buffalo New York USAUBMD Orthopaedics and Sports Medicine, Jacobs School of Medicine and Biomedical Sciences State University of New York at Buffalo Buffalo New York USADepartment of Rehabilitation Science School of Public Health and Health Professions, State University of New York at Buffalo Buffalo New York USADepartment of Rehabilitation Science School of Public Health and Health Professions, State University of New York at Buffalo Buffalo New York USAUBMD Orthopaedics and Sports Medicine, Jacobs School of Medicine and Biomedical Sciences State University of New York at Buffalo Buffalo New York USAAbstract Sport‐related concussion (SRC) is associated with cardiovascular autonomic nervous system (ANS) dysfunction. This study examines resting cardiovascular ANS activity in adolescents with SRC compared to controls early post‐injury and after clinical recovery, analyzing its correlation with symptom severity and recovery outcomes. Cardiovascular ANS function was evaluated using heart rate variability (HRV), systolic blood pressure variability (SBPV) and baroreflex sensitivity (BRS). Symptoms were assessed via the Post‐Concussion Symptom Scale, and recovery outcomes were categorized by recovery duration. Following acute SRC, no significant differences in HRV, SBPV or BRS were found between SRC and control groups, nor between those with delayed or normal recovery. Post‐recovery, SRC participants had higher low frequency (LF) SBPV than controls and their initial assessment. When concussed participants were symptomatic, LF SBPV correlated directly with overall, cognitive, and fatigue symptom severity, while high frequency (HF) HRV inversely correlated with affective symptoms (Spearman's rho: 0.4–0.6). Resting cardiovascular ANS function remains unchanged in adolescent athletes acutely after SRC, suggesting it has limited diagnostic and prognostic potential. Although some correlations between individual symptom domains and ANS activity were observed, they were not significantly different from asymptomatic controls, limiting the ability to interpret these findings.https://doi.org/10.14814/phy2.70114autonomic nervous systembrain concussionpost concussion symptom |
| spellingShingle | Wenjie Ji Haley M. Chizuk John J. Leddy Sue A. Sisto Mohammad N. Haider Symptom clusters and resting cardiovascular autonomic measures in adolescents: From acute concussion to recovery Physiological Reports autonomic nervous system brain concussion post concussion symptom |
| title | Symptom clusters and resting cardiovascular autonomic measures in adolescents: From acute concussion to recovery |
| title_full | Symptom clusters and resting cardiovascular autonomic measures in adolescents: From acute concussion to recovery |
| title_fullStr | Symptom clusters and resting cardiovascular autonomic measures in adolescents: From acute concussion to recovery |
| title_full_unstemmed | Symptom clusters and resting cardiovascular autonomic measures in adolescents: From acute concussion to recovery |
| title_short | Symptom clusters and resting cardiovascular autonomic measures in adolescents: From acute concussion to recovery |
| title_sort | symptom clusters and resting cardiovascular autonomic measures in adolescents from acute concussion to recovery |
| topic | autonomic nervous system brain concussion post concussion symptom |
| url | https://doi.org/10.14814/phy2.70114 |
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