Sexual dysfunction following low-dose-rate brachytherapy for prostate cancer
Prostate cancer (PCa) is one of the most prevalent forms of male malignancies globally, ranking second in terms of incidence and sixth in terms of mortality. Low-dose-rate brachytherapy (LDRT) represents a treatment modality for PCa, involving the implantation of permanent radioactive sources into t...
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| Format: | Article |
| Language: | Russian |
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Ministry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional Education
2025-01-01
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| Series: | Вестник урологии |
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| Online Access: | https://www.urovest.ru/jour/article/view/979 |
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| author | A. D. Anosov M. E. Efremov V. L. Medvedev M. I. Kogan |
| author_facet | A. D. Anosov M. E. Efremov V. L. Medvedev M. I. Kogan |
| author_sort | A. D. Anosov |
| collection | DOAJ |
| description | Prostate cancer (PCa) is one of the most prevalent forms of male malignancies globally, ranking second in terms of incidence and sixth in terms of mortality. Low-dose-rate brachytherapy (LDRT) represents a treatment modality for PCa, involving the implantation of permanent radioactive sources into the prostate tissue. The isotopes predominantly utilised are I–125 and Pd–103. LDRT demonstrates high rates of biochemical and clinical relapse-free survival, with cancer-specific and overall survival rates comparable to those achieved through radical prostatectomy. Despite the advantages associated with LDRT, evidence has accumulated regarding the potential complications accompanying this treatment approach, including sexual dysfunction and erectile dysfunction. Sexual satisfaction constitutes a critical concern for men undergoing PCa treatment. It is essential that both the patient and the healthcare provider prioritise not only erectile function but also the preservation of sexuality in its entirety. The present study endeavours to evaluate the accumulated material on the topic of diagnosing and treating sexual dysfunctions following low-dose-rate brachytherapy (LDRT). The analysis encompassed articles by foreign and domestic authors published between 2014 and 2024, as well as fundamental articles and literature dating back earlier. These works were devoted to sexual dysfunction, assessment, and rehabilitation of sexual function in patients with PCa who underwent LDRT. Our review confirmed the existing necessity for a detailed study of rational methods for diagnosing sexual dysfunctions prior to selecting a treatment method, as well as the possible prevention of disorders after LDRT. It is also essential to develop sexual and penile rehabilitation strategies following LDRT for PCa, which is currently widely employed. |
| format | Article |
| id | doaj-art-0d54e3eb7ff041409c8d6fd7cf7062fa |
| institution | Kabale University |
| issn | 2308-6424 |
| language | Russian |
| publishDate | 2025-01-01 |
| publisher | Ministry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional Education |
| record_format | Article |
| series | Вестник урологии |
| spelling | doaj-art-0d54e3eb7ff041409c8d6fd7cf7062fa2025-08-20T03:43:33ZrusMinistry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional EducationВестник урологии2308-64242025-01-01126455110.21886/2308-6424-2024-12-6-45-51576Sexual dysfunction following low-dose-rate brachytherapy for prostate cancerA. D. Anosov0M. E. Efremov1V. L. Medvedev2M. I. Kogan3Kuban State Medical University; Research Institute — Ochapovsky Krasnodar Regional Clinical Hospital No.1Kuban State Medical University; Research Institute — Ochapovsky Krasnodar Regional Clinical Hospital No.1Kuban State Medical University; Research Institute — Ochapovsky Krasnodar Regional Clinical Hospital No.1Rostov State Medical UniversityProstate cancer (PCa) is one of the most prevalent forms of male malignancies globally, ranking second in terms of incidence and sixth in terms of mortality. Low-dose-rate brachytherapy (LDRT) represents a treatment modality for PCa, involving the implantation of permanent radioactive sources into the prostate tissue. The isotopes predominantly utilised are I–125 and Pd–103. LDRT demonstrates high rates of biochemical and clinical relapse-free survival, with cancer-specific and overall survival rates comparable to those achieved through radical prostatectomy. Despite the advantages associated with LDRT, evidence has accumulated regarding the potential complications accompanying this treatment approach, including sexual dysfunction and erectile dysfunction. Sexual satisfaction constitutes a critical concern for men undergoing PCa treatment. It is essential that both the patient and the healthcare provider prioritise not only erectile function but also the preservation of sexuality in its entirety. The present study endeavours to evaluate the accumulated material on the topic of diagnosing and treating sexual dysfunctions following low-dose-rate brachytherapy (LDRT). The analysis encompassed articles by foreign and domestic authors published between 2014 and 2024, as well as fundamental articles and literature dating back earlier. These works were devoted to sexual dysfunction, assessment, and rehabilitation of sexual function in patients with PCa who underwent LDRT. Our review confirmed the existing necessity for a detailed study of rational methods for diagnosing sexual dysfunctions prior to selecting a treatment method, as well as the possible prevention of disorders after LDRT. It is also essential to develop sexual and penile rehabilitation strategies following LDRT for PCa, which is currently widely employed.https://www.urovest.ru/jour/article/view/979prostate cancerlow-dose-rate brachytherapysexual dysfunctionerectile dysfunctionsexual rehabilitationpenile rehabilitation |
| spellingShingle | A. D. Anosov M. E. Efremov V. L. Medvedev M. I. Kogan Sexual dysfunction following low-dose-rate brachytherapy for prostate cancer Вестник урологии prostate cancer low-dose-rate brachytherapy sexual dysfunction erectile dysfunction sexual rehabilitation penile rehabilitation |
| title | Sexual dysfunction following low-dose-rate brachytherapy for prostate cancer |
| title_full | Sexual dysfunction following low-dose-rate brachytherapy for prostate cancer |
| title_fullStr | Sexual dysfunction following low-dose-rate brachytherapy for prostate cancer |
| title_full_unstemmed | Sexual dysfunction following low-dose-rate brachytherapy for prostate cancer |
| title_short | Sexual dysfunction following low-dose-rate brachytherapy for prostate cancer |
| title_sort | sexual dysfunction following low dose rate brachytherapy for prostate cancer |
| topic | prostate cancer low-dose-rate brachytherapy sexual dysfunction erectile dysfunction sexual rehabilitation penile rehabilitation |
| url | https://www.urovest.ru/jour/article/view/979 |
| work_keys_str_mv | AT adanosov sexualdysfunctionfollowinglowdoseratebrachytherapyforprostatecancer AT meefremov sexualdysfunctionfollowinglowdoseratebrachytherapyforprostatecancer AT vlmedvedev sexualdysfunctionfollowinglowdoseratebrachytherapyforprostatecancer AT mikogan sexualdysfunctionfollowinglowdoseratebrachytherapyforprostatecancer |