The global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors: a systematic review and meta-analysis
Abstract Background Mild cognitive impairment (MCI) is a common disorder among the geriatric population (GP). MCI induces adverse effects on life quality by disrupting of natural aging process, daily activities, and memory. This systematic review and meta-analysis study aimed to investigate the glob...
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BMC
2025-05-01
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| Series: | BMC Geriatrics |
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| Online Access: | https://doi.org/10.1186/s12877-025-05967-w |
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| author | Nader Salari Fateme Lotfi Amir Abdolmaleki Pegah Heidarian Shabnam Rasoulpoor Jalil Fazeli Hadi Najafi Masoud Mohammadi |
| author_facet | Nader Salari Fateme Lotfi Amir Abdolmaleki Pegah Heidarian Shabnam Rasoulpoor Jalil Fazeli Hadi Najafi Masoud Mohammadi |
| author_sort | Nader Salari |
| collection | DOAJ |
| description | Abstract Background Mild cognitive impairment (MCI) is a common disorder among the geriatric population (GP). MCI induces adverse effects on life quality by disrupting of natural aging process, daily activities, and memory. This systematic review and meta-analysis study aimed to investigate the global prevalence of MCI in GP with an emphasis on associated influential factors. Methods Electronic databases of PubMed, Scopus, WoS, Embase, ScienceDirect, and Google Scholar were systematically searched (by November 2024) using the MeSH-based keywords. Collected references were imported into the Citation Management Software of EndNote (v.8) for duplicate detection. Paper screenings and quality assessments were applied based on the inclusion and exclusion criteria. Then, eligible papers were gathered and data analysis was performed using CMA software (v.2). Results In the review of 51 eligible studies (n = 287,689 elderly individuals), the global prevalence of mild cognitive impairment in geriatric population was found 23.7% (95%CI:18.6–29.6). According to the meta-regression analysis, following the increase in sample size and year of paper publication, the mild cognitive impairment index decreased and increased, respectively. Besides, age, educational level, and depression status were considered the most critical influential factors of mild cognitive impairment in geriatric population. Conclusion According to the relatively high prevalence of mild cognitive impairment in geriatric population, determination of proper health strategies seems necessary for diagnosis and treatment of mild cognitive impairment along with awareness and management of associated consequences in geriatric population. Clinical trial number Not applicable. |
| format | Article |
| id | doaj-art-0d4f135d15a94ce88df83f7070aa3327 |
| institution | OA Journals |
| issn | 1471-2318 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj-art-0d4f135d15a94ce88df83f7070aa33272025-08-20T01:49:43ZengBMCBMC Geriatrics1471-23182025-05-0125111410.1186/s12877-025-05967-wThe global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors: a systematic review and meta-analysisNader Salari0Fateme Lotfi1Amir Abdolmaleki2Pegah Heidarian3Shabnam Rasoulpoor4Jalil Fazeli5Hadi Najafi6Masoud Mohammadi7Department of Biostatistics, School of Health, Kermanshah University of Medical SciencesStudent Research Committee, Kermanshah University of Medical SciencesDepartment of Operating Room, Nahavand School of Allied Medical Sciences, Hamadan University of Medical SciencesStudent Research Committee, Kermanshah University of Medical SciencesDepartment of Nursing, School of Nursing and Midwifery, Urmia University of Medical SciencesOccupational Sleep Research Center, Tehran University of Medical SciencesDepartment of Geriatric Health, School of Medicine, Tehran University of Medical SciencesResearch Center for Social Determinants of Health, Jahrom University of Medical SciencesAbstract Background Mild cognitive impairment (MCI) is a common disorder among the geriatric population (GP). MCI induces adverse effects on life quality by disrupting of natural aging process, daily activities, and memory. This systematic review and meta-analysis study aimed to investigate the global prevalence of MCI in GP with an emphasis on associated influential factors. Methods Electronic databases of PubMed, Scopus, WoS, Embase, ScienceDirect, and Google Scholar were systematically searched (by November 2024) using the MeSH-based keywords. Collected references were imported into the Citation Management Software of EndNote (v.8) for duplicate detection. Paper screenings and quality assessments were applied based on the inclusion and exclusion criteria. Then, eligible papers were gathered and data analysis was performed using CMA software (v.2). Results In the review of 51 eligible studies (n = 287,689 elderly individuals), the global prevalence of mild cognitive impairment in geriatric population was found 23.7% (95%CI:18.6–29.6). According to the meta-regression analysis, following the increase in sample size and year of paper publication, the mild cognitive impairment index decreased and increased, respectively. Besides, age, educational level, and depression status were considered the most critical influential factors of mild cognitive impairment in geriatric population. Conclusion According to the relatively high prevalence of mild cognitive impairment in geriatric population, determination of proper health strategies seems necessary for diagnosis and treatment of mild cognitive impairment along with awareness and management of associated consequences in geriatric population. Clinical trial number Not applicable.https://doi.org/10.1186/s12877-025-05967-wMild cognitive impairmentElderlyMeta-analysis |
| spellingShingle | Nader Salari Fateme Lotfi Amir Abdolmaleki Pegah Heidarian Shabnam Rasoulpoor Jalil Fazeli Hadi Najafi Masoud Mohammadi The global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors: a systematic review and meta-analysis BMC Geriatrics Mild cognitive impairment Elderly Meta-analysis |
| title | The global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors: a systematic review and meta-analysis |
| title_full | The global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors: a systematic review and meta-analysis |
| title_fullStr | The global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors: a systematic review and meta-analysis |
| title_full_unstemmed | The global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors: a systematic review and meta-analysis |
| title_short | The global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors: a systematic review and meta-analysis |
| title_sort | global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors a systematic review and meta analysis |
| topic | Mild cognitive impairment Elderly Meta-analysis |
| url | https://doi.org/10.1186/s12877-025-05967-w |
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