Impact of memory T cells on SARS-CoV-2 vaccine response in hematopoietic stem cell transplant.

Impact of memory T cells on SARS-CoV-2 vaccine response in hematopoietic stem cell transplant.

During the COVID-19 pandemic, hematopoietic stem cell transplant (HSCT) recipients had elevated mortality rates from SARS-CoV-2 infection, ranging between 10-40%. SARS-CoV-2 mRNA vaccines are important tools in preventing severe disease, yet their efficacy post-transplant remains unclear, especially...

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Main Authors: Jennifer VanOudenhove, Yuxin Liu, Raman Nelakanti, Dongjoo Kim, Emma Busarello, Natalia Tijaro Ovalle, Zhihong Qi, Padmavathi Mamillapalli, Alexa Siddon, Zhiliang Bai, Alfredo Axtmayer, Cheryl Corso, Shalin Kothari, Francine Foss, Iris Isufi, Toma Tebaldi, Lohith Gowda, Rong Fan, Stuart Seropian, Stephanie Halene
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0320744
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