Head-to-Head Comparison of UHPLC-MS/MS and Alinity C for Plasma Analysis of Risperidone and Paliperidone

Head-to-Head Comparison of UHPLC-MS/MS and Alinity C for Plasma Analysis of Risperidone and Paliperidone

<b>Background and objectives:</b> Risperidone, a second-generation antipsychotic widely used in the treatment of schizophrenia, requires therapeutic drug monitoring due to its high interindividual variability. UHPLC-MS/MS is considered the gold standard for pharmacokinetic studies owing...

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Main Authors: Francisco José Toja-Camba, Gonzalo Hermelo-Vidal, Carolina Feitosa-Medeiros, María Vidal-Millares, María José Durán-Maseda, Anxo Fernández-Ferreiro, Cristina Mondelo-García
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Pharmaceuticals
Subjects:
risperidone
paliperidone
UHPLC-MS/MS
Alinity C
pharmacokinetics
TDM
Online Access:https://www.mdpi.com/1424-8247/17/11/1446
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