The emerging role of Nrf2 in dermatotoxicology
Abstract The nuclear factor erythroid 2‐related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2‐prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel molecular insights i...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Springer Nature
2014-02-01
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| Series: | EMBO Molecular Medicine |
| Online Access: | https://doi.org/10.1002/emmm.201303797 |
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| _version_ | 1850203444904722432 |
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| author | Nguan S Tan Walter Wahli |
| author_facet | Nguan S Tan Walter Wahli |
| author_sort | Nguan S Tan |
| collection | DOAJ |
| description | Abstract The nuclear factor erythroid 2‐related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2‐prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel molecular insights into poison‐induced chloracne and metabolizing acquired dioxin‐induced skin hamartomas or MADISH. |
| format | Article |
| id | doaj-art-0d228c1970bc4e2195e52ea05bfb16d4 |
| institution | OA Journals |
| issn | 1757-4676 1757-4684 |
| language | English |
| publishDate | 2014-02-01 |
| publisher | Springer Nature |
| record_format | Article |
| series | EMBO Molecular Medicine |
| spelling | doaj-art-0d228c1970bc4e2195e52ea05bfb16d42025-08-20T02:11:30ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842014-02-016443143310.1002/emmm.201303797The emerging role of Nrf2 in dermatotoxicologyNguan S Tan0Walter Wahli1School of Biological Sciences, Nanyang Technological UniversityLee Kong Chian School of Medicine, Nanyang Technological University, Singapore General HospitalAbstract The nuclear factor erythroid 2‐related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine, Nrf2‐prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel molecular insights into poison‐induced chloracne and metabolizing acquired dioxin‐induced skin hamartomas or MADISH.https://doi.org/10.1002/emmm.201303797 |
| spellingShingle | Nguan S Tan Walter Wahli The emerging role of Nrf2 in dermatotoxicology EMBO Molecular Medicine |
| title | The emerging role of Nrf2 in dermatotoxicology |
| title_full | The emerging role of Nrf2 in dermatotoxicology |
| title_fullStr | The emerging role of Nrf2 in dermatotoxicology |
| title_full_unstemmed | The emerging role of Nrf2 in dermatotoxicology |
| title_short | The emerging role of Nrf2 in dermatotoxicology |
| title_sort | emerging role of nrf2 in dermatotoxicology |
| url | https://doi.org/10.1002/emmm.201303797 |
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