Treatment outcomes of pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy in malignant glaucoma in a tertiary eye care center in South India

Purpose: To report the clinical profile and treatment outcomes of malignant glaucoma and the efficacy of pars plana vitrectomy-hyaloidotomy-zonulectomy and iridectomy in Indian eyes. Design: Retrospective observational study. Methods: The study was a retrospective chart review. Medical records of pa...

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Main Authors: Mrunali M Dhavalikar, M Manju, Ganesh V Raman, Premanand Chandran, Prema Subramaniam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-06-01
Series:Indian Journal of Ophthalmology
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Online Access:https://journals.lww.com/10.4103/IJO.IJO_1556_24
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author Mrunali M Dhavalikar
M Manju
Ganesh V Raman
Premanand Chandran
Prema Subramaniam
author_facet Mrunali M Dhavalikar
M Manju
Ganesh V Raman
Premanand Chandran
Prema Subramaniam
author_sort Mrunali M Dhavalikar
collection DOAJ
description Purpose: To report the clinical profile and treatment outcomes of malignant glaucoma and the efficacy of pars plana vitrectomy-hyaloidotomy-zonulectomy and iridectomy in Indian eyes. Design: Retrospective observational study. Methods: The study was a retrospective chart review. Medical records of patients diagnosed with malignant glaucoma between December 2018 and August 2022 were reviewed. Patients with the diagnosis of malignant glaucoma and those who underwent pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy were included in the study. Patients with less than 3 months of follow-up were excluded from the study. Data collected included demographic data, primary ocular procedure, best-corrected visual acuity in logMAR, and lens status. The data also included intraocular pressure and number of antiglaucoma medications used at the time of presentation and during follow-ups. Results: The final analysis included 36 eyes of 30 patients. There was a statistically significant reduction of intraocular pressure at each visit (P value = 0.001) and in the number of antiglaucoma medications (P value < 0.001). A total of 29 eyes had a follow-up of 6 months, 19 eyes (65.5%) had a complete success, and 10 eyes (34.4%) had qualified success at the end of 6 months. Conclusion: Pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy surgery has favorable outcomes in eyes with malignant glaucoma.
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1998-3689
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publishDate 2025-06-01
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spelling doaj-art-0d1f5317b9d54d0fabdf7cc636cc012e2025-08-20T03:29:21ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-06-0173Suppl 3S444S44810.4103/IJO.IJO_1556_24Treatment outcomes of pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy in malignant glaucoma in a tertiary eye care center in South IndiaMrunali M DhavalikarM ManjuGanesh V RamanPremanand ChandranPrema SubramaniamPurpose: To report the clinical profile and treatment outcomes of malignant glaucoma and the efficacy of pars plana vitrectomy-hyaloidotomy-zonulectomy and iridectomy in Indian eyes. Design: Retrospective observational study. Methods: The study was a retrospective chart review. Medical records of patients diagnosed with malignant glaucoma between December 2018 and August 2022 were reviewed. Patients with the diagnosis of malignant glaucoma and those who underwent pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy were included in the study. Patients with less than 3 months of follow-up were excluded from the study. Data collected included demographic data, primary ocular procedure, best-corrected visual acuity in logMAR, and lens status. The data also included intraocular pressure and number of antiglaucoma medications used at the time of presentation and during follow-ups. Results: The final analysis included 36 eyes of 30 patients. There was a statistically significant reduction of intraocular pressure at each visit (P value = 0.001) and in the number of antiglaucoma medications (P value < 0.001). A total of 29 eyes had a follow-up of 6 months, 19 eyes (65.5%) had a complete success, and 10 eyes (34.4%) had qualified success at the end of 6 months. Conclusion: Pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy surgery has favorable outcomes in eyes with malignant glaucoma.https://journals.lww.com/10.4103/IJO.IJO_1556_24aqueous misdirection syndromemalignant glaucomapars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy
spellingShingle Mrunali M Dhavalikar
M Manju
Ganesh V Raman
Premanand Chandran
Prema Subramaniam
Treatment outcomes of pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy in malignant glaucoma in a tertiary eye care center in South India
Indian Journal of Ophthalmology
aqueous misdirection syndrome
malignant glaucoma
pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy
title Treatment outcomes of pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy in malignant glaucoma in a tertiary eye care center in South India
title_full Treatment outcomes of pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy in malignant glaucoma in a tertiary eye care center in South India
title_fullStr Treatment outcomes of pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy in malignant glaucoma in a tertiary eye care center in South India
title_full_unstemmed Treatment outcomes of pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy in malignant glaucoma in a tertiary eye care center in South India
title_short Treatment outcomes of pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy in malignant glaucoma in a tertiary eye care center in South India
title_sort treatment outcomes of pars plana vitrectomy hyaloidotomy zonulectomy iridectomy in malignant glaucoma in a tertiary eye care center in south india
topic aqueous misdirection syndrome
malignant glaucoma
pars plana vitrectomy-hyaloidotomy-zonulectomy-iridectomy
url https://journals.lww.com/10.4103/IJO.IJO_1556_24
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