Successful Management of Repetitive Urinary Obstruction and Anuria Caused by Double J Stent Calculi Formation after Renal Transplantation

This report firstly describes an extremely rare case of repetitive double J stent calculi formation after renal transplantation caused by the antihyperparathyroidism (HPT) drug calcitriol. In 2012, a woman initially presented to our hospital for anuria with lower abdominal pain. She was diagnosed wi...

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Main Authors: Zongyao Hao, Li Zhang, Jun Zhou, Xiansheng Zhang, Haoqiang Shi, Yifei Zhang, Pengfei Wei, Chaozhao Liang
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2014/245724
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author Zongyao Hao
Li Zhang
Jun Zhou
Xiansheng Zhang
Haoqiang Shi
Yifei Zhang
Pengfei Wei
Chaozhao Liang
author_facet Zongyao Hao
Li Zhang
Jun Zhou
Xiansheng Zhang
Haoqiang Shi
Yifei Zhang
Pengfei Wei
Chaozhao Liang
author_sort Zongyao Hao
collection DOAJ
description This report firstly describes an extremely rare case of repetitive double J stent calculi formation after renal transplantation caused by the antihyperparathyroidism (HPT) drug calcitriol. In 2012, a woman initially presented to our hospital for anuria with lower abdominal pain. She was diagnosed with allograft hydronephrosis and double J stents obstruction by calculi formation after transplantation and treated with triplicate stents replacements in another hospital without clinical manifestations improvements. Through detailed exploration of medical history, we conclude that the abnormal calculi formation is due to the calcitriol (1,25-dihydroxyvitamin D3) administration, a drug which can increase renal tubular reabsorption of calcium for treating posttransplant HPT bone disease. After discontinuing calcitriol, the patient was stone-free and had a good recovery without severe complications during the 9-month follow-up. Our novel findings may provide an important clue and approach to managing formidable repetitive double J stent calculi formation in the clinical trial.
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id doaj-art-0d1e9b5bb3634d40ad3a71e76c3962cd
institution Kabale University
issn 2090-6943
2090-6951
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Case Reports in Transplantation
spelling doaj-art-0d1e9b5bb3634d40ad3a71e76c3962cd2025-08-20T03:54:15ZengWileyCase Reports in Transplantation2090-69432090-69512014-01-01201410.1155/2014/245724245724Successful Management of Repetitive Urinary Obstruction and Anuria Caused by Double J Stent Calculi Formation after Renal TransplantationZongyao Hao0Li Zhang1Jun Zhou2Xiansheng Zhang3Haoqiang Shi4Yifei Zhang5Pengfei Wei6Chaozhao Liang7Department of Urology, The First Affiliated Hospital of Anhui Medical University and Institute of Urology, Anhui Medical University, Hefei, Anhui 230022, ChinaDepartment of Urology, The First Affiliated Hospital of Anhui Medical University and Institute of Urology, Anhui Medical University, Hefei, Anhui 230022, ChinaDepartment of Urology, The First Affiliated Hospital of Anhui Medical University and Institute of Urology, Anhui Medical University, Hefei, Anhui 230022, ChinaDepartment of Urology, The First Affiliated Hospital of Anhui Medical University and Institute of Urology, Anhui Medical University, Hefei, Anhui 230022, ChinaDepartment of Urology, The First Affiliated Hospital of Anhui Medical University and Institute of Urology, Anhui Medical University, Hefei, Anhui 230022, ChinaDepartment of Urology, The First Affiliated Hospital of Anhui Medical University and Institute of Urology, Anhui Medical University, Hefei, Anhui 230022, ChinaSchool of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, ChinaDepartment of Urology, The First Affiliated Hospital of Anhui Medical University and Institute of Urology, Anhui Medical University, Hefei, Anhui 230022, ChinaThis report firstly describes an extremely rare case of repetitive double J stent calculi formation after renal transplantation caused by the antihyperparathyroidism (HPT) drug calcitriol. In 2012, a woman initially presented to our hospital for anuria with lower abdominal pain. She was diagnosed with allograft hydronephrosis and double J stents obstruction by calculi formation after transplantation and treated with triplicate stents replacements in another hospital without clinical manifestations improvements. Through detailed exploration of medical history, we conclude that the abnormal calculi formation is due to the calcitriol (1,25-dihydroxyvitamin D3) administration, a drug which can increase renal tubular reabsorption of calcium for treating posttransplant HPT bone disease. After discontinuing calcitriol, the patient was stone-free and had a good recovery without severe complications during the 9-month follow-up. Our novel findings may provide an important clue and approach to managing formidable repetitive double J stent calculi formation in the clinical trial.http://dx.doi.org/10.1155/2014/245724
spellingShingle Zongyao Hao
Li Zhang
Jun Zhou
Xiansheng Zhang
Haoqiang Shi
Yifei Zhang
Pengfei Wei
Chaozhao Liang
Successful Management of Repetitive Urinary Obstruction and Anuria Caused by Double J Stent Calculi Formation after Renal Transplantation
Case Reports in Transplantation
title Successful Management of Repetitive Urinary Obstruction and Anuria Caused by Double J Stent Calculi Formation after Renal Transplantation
title_full Successful Management of Repetitive Urinary Obstruction and Anuria Caused by Double J Stent Calculi Formation after Renal Transplantation
title_fullStr Successful Management of Repetitive Urinary Obstruction and Anuria Caused by Double J Stent Calculi Formation after Renal Transplantation
title_full_unstemmed Successful Management of Repetitive Urinary Obstruction and Anuria Caused by Double J Stent Calculi Formation after Renal Transplantation
title_short Successful Management of Repetitive Urinary Obstruction and Anuria Caused by Double J Stent Calculi Formation after Renal Transplantation
title_sort successful management of repetitive urinary obstruction and anuria caused by double j stent calculi formation after renal transplantation
url http://dx.doi.org/10.1155/2014/245724
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