Evaluation of Some Material to inhibit Biofilm Formed by Acinetobacter baumannii Isolates
The study has included the ability of Acinetobacter baumannii (isolated from clinical infections and hospital environment) to form a biofilm and investigated the possibility of inhibition this biofilm by using some materials: EDTA, five amino acids and five plant extracts. The results showed tha...
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| Format: | Article |
| Language: | English |
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Tikrit University
2019-08-01
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| Series: | Tikrit Journal of Pure Science |
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| Online Access: | https://tjpsj.org/index.php/tjps/article/view/391 |
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| _version_ | 1849320706121138176 |
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| author | Noor Hussein Ahmad Ghada A. Mohammad |
| author_facet | Noor Hussein Ahmad Ghada A. Mohammad |
| author_sort | Noor Hussein Ahmad |
| collection | DOAJ |
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The study has included the ability of Acinetobacter baumannii (isolated from clinical infections and hospital environment) to form a biofilm and investigated the possibility of inhibition this biofilm by using some materials: EDTA, five amino acids and five plant extracts.
The results showed that all isolates of A.baumannii had a good ability to form the biofilm (100%). Four isolates which had strong former of biofilm which were selected as well as a standard isolate (A. baumannii ATCC19606). The inhibitory effect on biofilm formation was investigated. EDTA had a good inhibitory effect, also, all amino acids showed good inhibitory activity , with the best inhibition in Glutamic acid at a concentration of 50 mM, while plant extracts varied in their inhibition ratio to inhibit the biofilm, turmeric, cloves and rosemary had a good inhibitory effect, Bay leaf has the ability to inhibit the biofilm formation but less than others, while the plant extract of the Myrtle did not show any inhibition activity.
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| format | Article |
| id | doaj-art-0d1d1c905a7740ddaec2cfaf5bb0fde6 |
| institution | Kabale University |
| issn | 1813-1662 2415-1726 |
| language | English |
| publishDate | 2019-08-01 |
| publisher | Tikrit University |
| record_format | Article |
| series | Tikrit Journal of Pure Science |
| spelling | doaj-art-0d1d1c905a7740ddaec2cfaf5bb0fde62025-08-20T03:50:00ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262019-08-0124410.25130/tjps.v24i4.391Evaluation of Some Material to inhibit Biofilm Formed by Acinetobacter baumannii IsolatesNoor Hussein AhmadGhada A. Mohammad The study has included the ability of Acinetobacter baumannii (isolated from clinical infections and hospital environment) to form a biofilm and investigated the possibility of inhibition this biofilm by using some materials: EDTA, five amino acids and five plant extracts. The results showed that all isolates of A.baumannii had a good ability to form the biofilm (100%). Four isolates which had strong former of biofilm which were selected as well as a standard isolate (A. baumannii ATCC19606). The inhibitory effect on biofilm formation was investigated. EDTA had a good inhibitory effect, also, all amino acids showed good inhibitory activity , with the best inhibition in Glutamic acid at a concentration of 50 mM, while plant extracts varied in their inhibition ratio to inhibit the biofilm, turmeric, cloves and rosemary had a good inhibitory effect, Bay leaf has the ability to inhibit the biofilm formation but less than others, while the plant extract of the Myrtle did not show any inhibition activity. https://tjpsj.org/index.php/tjps/article/view/391Acinetobacter baumanniiBiofilm formationAntibiofilm compounds |
| spellingShingle | Noor Hussein Ahmad Ghada A. Mohammad Evaluation of Some Material to inhibit Biofilm Formed by Acinetobacter baumannii Isolates Tikrit Journal of Pure Science Acinetobacter baumannii Biofilm formation Antibiofilm compounds |
| title | Evaluation of Some Material to inhibit Biofilm Formed by Acinetobacter baumannii Isolates |
| title_full | Evaluation of Some Material to inhibit Biofilm Formed by Acinetobacter baumannii Isolates |
| title_fullStr | Evaluation of Some Material to inhibit Biofilm Formed by Acinetobacter baumannii Isolates |
| title_full_unstemmed | Evaluation of Some Material to inhibit Biofilm Formed by Acinetobacter baumannii Isolates |
| title_short | Evaluation of Some Material to inhibit Biofilm Formed by Acinetobacter baumannii Isolates |
| title_sort | evaluation of some material to inhibit biofilm formed by acinetobacter baumannii isolates |
| topic | Acinetobacter baumannii Biofilm formation Antibiofilm compounds |
| url | https://tjpsj.org/index.php/tjps/article/view/391 |
| work_keys_str_mv | AT noorhusseinahmad evaluationofsomematerialtoinhibitbiofilmformedbyacinetobacterbaumanniiisolates AT ghadaamohammad evaluationofsomematerialtoinhibitbiofilmformedbyacinetobacterbaumanniiisolates |