Polymorphonuclear myeloid-derived suppressor cells regulates immune recovery during HIV infection through PD-L1 and TGF-β pathways

Polymorphonuclear myeloid-derived suppressor cells regulates immune recovery during HIV infection through PD-L1 and TGF-β pathways

BackgroundAlthough MDSCs are widely recognized for their immunoinhibitory effects in pathological conditions, their function during HIV infection particularly within the mechanisms underlying incomplete immune recovery remains elusive.MethodsWe conducted a cross-sectional study in which 30 healthy c...

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Bibliographic Details
Main Authors: Zihua Wang, Yue Hu, Jing Song, Ping Ma, Huan Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
HIV
MDSC
PD-L1
TGF-β
immune recovery
immunological non-responders
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1516421/full
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