Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis

The nontraumatic perforations of the small intestine are pathological entities with particular aspects in respect to diagnosis and treatment. These peculiarities derive from the nonspecific clinical expression of the peritonitis syndrome, and from the multitude of causes that might be the primary so...

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Main Authors: Petrişor Banu, Vlad D. Constantin, Florian Popa, Mihaela F. Nistor
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Journal of Mind and Medical Sciences
Subjects:
Online Access:http://scholar.valpo.edu/cgi/viewcontent.cgi?article=1029&context=jmms
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author Petrişor Banu
Vlad D. Constantin
Florian Popa
Mihaela F. Nistor
author_facet Petrişor Banu
Vlad D. Constantin
Florian Popa
Mihaela F. Nistor
author_sort Petrişor Banu
collection DOAJ
description The nontraumatic perforations of the small intestine are pathological entities with particular aspects in respect to diagnosis and treatment. These peculiarities derive from the nonspecific clinical expression of the peritonitis syndrome, and from the multitude of causes that might be the primary sources of the perforation: foreign bodies, inflammatory diseases, tumors, infectious diseases, etc. Accordingly, in most cases intestinal perforation is discovered only by laparotomy and the definitive diagnosis is available only after histopathologic examination. Small bowel malignancies are rare; among them, lymphomas rank third in frequency, being mostly B-cell non Hodgkin lymphomas. Only 10% of non-Hodgkin lymphomas are with T-cell. We report the case of a 57 years’ old woman with intestinal T-cell lymphoma, whose first clinical symptomatology was related to a complication represented by perforation of the small intestine. Laparotomy performed in emergency identified an ulcerative lesion with perforation in the jejunum, which required segmental enterectomy with anastomosis. The nonspecific clinical manifestations of intestinal lymphomas make from diagnosis a difficult procedure. Due to the fact that surgery does not have a definite place in the treatment of the small intestinal lymphomas (for cases complicated with perforation), and beyond the morbidity associated with the surgery performed in emergency conditions, prognosis of these patients is finally given by the possibility to control the systemic disease through adjuvant therapy.
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spelling doaj-art-0d1914727bfd4f95b5cd9c2e7e7f6d042025-08-20T03:09:51ZengMDPI AGJournal of Mind and Medical Sciences2392-76742392-76742016-04-01318898Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitisPetrişor Banu0Vlad D. Constantin1Florian Popa2Mihaela F. Nistor3Carol Davila University, Department of Surgery, St. Pantelimon Hospital, Department of SurgeryCarol Davila University, Department of Surgery, St. Pantelimon Hospital, Department of SurgeryCarol Davila University, Department of Surgery, St. Pantelimon Hospital, Department of SurgerySt. Pantelimon Hospital, Department of SurgeryThe nontraumatic perforations of the small intestine are pathological entities with particular aspects in respect to diagnosis and treatment. These peculiarities derive from the nonspecific clinical expression of the peritonitis syndrome, and from the multitude of causes that might be the primary sources of the perforation: foreign bodies, inflammatory diseases, tumors, infectious diseases, etc. Accordingly, in most cases intestinal perforation is discovered only by laparotomy and the definitive diagnosis is available only after histopathologic examination. Small bowel malignancies are rare; among them, lymphomas rank third in frequency, being mostly B-cell non Hodgkin lymphomas. Only 10% of non-Hodgkin lymphomas are with T-cell. We report the case of a 57 years’ old woman with intestinal T-cell lymphoma, whose first clinical symptomatology was related to a complication represented by perforation of the small intestine. Laparotomy performed in emergency identified an ulcerative lesion with perforation in the jejunum, which required segmental enterectomy with anastomosis. The nonspecific clinical manifestations of intestinal lymphomas make from diagnosis a difficult procedure. Due to the fact that surgery does not have a definite place in the treatment of the small intestinal lymphomas (for cases complicated with perforation), and beyond the morbidity associated with the surgery performed in emergency conditions, prognosis of these patients is finally given by the possibility to control the systemic disease through adjuvant therapy.http://scholar.valpo.edu/cgi/viewcontent.cgi?article=1029&context=jmmsperforationsmall intestineT-cell lymphomaperitonitis
spellingShingle Petrişor Banu
Vlad D. Constantin
Florian Popa
Mihaela F. Nistor
Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis
Journal of Mind and Medical Sciences
perforation
small intestine
T-cell lymphoma
peritonitis
title Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis
title_full Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis
title_fullStr Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis
title_full_unstemmed Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis
title_short Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis
title_sort perforated small intestine in a patient with t cell lymphoma a rare cause of peritonitis
topic perforation
small intestine
T-cell lymphoma
peritonitis
url http://scholar.valpo.edu/cgi/viewcontent.cgi?article=1029&context=jmms
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AT vladdconstantin perforatedsmallintestineinapatientwithtcelllymphomaararecauseofperitonitis
AT florianpopa perforatedsmallintestineinapatientwithtcelllymphomaararecauseofperitonitis
AT mihaelafnistor perforatedsmallintestineinapatientwithtcelllymphomaararecauseofperitonitis