In silico approach in the development of structural analogues of resveratrol with improved distribution in the central nervous system
Resveratrol exerts neuroprotective effects that are not only due to anti inflammatory and antioxidant activity but also by launched biogenesis via sirtuin-1 (SIRT1) protein that protects cells from oxidative stress. Resveratrol has low bioavailability due to low aqueous solubility and rapid metaboli...
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Main Authors: | Mitrović Darko, Pavlović Nebojša |
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Format: | Article |
Language: | English |
Published: |
University of Kragujevac, Faculty of Science
2024-01-01
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Series: | Kragujevac Journal of Science |
Subjects: | |
Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1450-9636/2024/1450-96362401059M.pdf |
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