Antibiotic screening of urine culture as a useful quality audit

Introduction: The diagnosis of urinary tract infections includes microbiologic culture of urine to determine the etiology of the infection. However, interpretation of the results can be confounded by various factors including the accuracy of a patient's history of current antibiotic usage. ...

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Main Authors: Godwin Wilson, Shaherudeen Badarudeen, Angela Godwin
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2011-02-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/923
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author Godwin Wilson
Shaherudeen Badarudeen
Angela Godwin
author_facet Godwin Wilson
Shaherudeen Badarudeen
Angela Godwin
author_sort Godwin Wilson
collection DOAJ
description Introduction: The diagnosis of urinary tract infections includes microbiologic culture of urine to determine the etiology of the infection. However, interpretation of the results can be confounded by various factors including the accuracy of a patient's history of current antibiotic usage.  Methodology: In this report, we tested urine specimens for the presence of antibiotics and compared our results to the accuracy of antibiotic data entry on the accompanying request forms. In addition, the consequences of culturing urine specimens with incomplete antibiotic history received in the laboratory were investigated. Results: During the study period, 14,680 urines were obtained and tested with a modified urine antibacterial substance assay (UABA). There were (97.32%) true-negative, 6 (0.04%) false-negative, 222 (1.51%) true-positive and 166 (1.13%) false-positive results. The sensitivity and specificity of this test was 97.37% and 98.85% respectively. Conclusion: This internal audit practice demonstrates the importance of accurately completed request forms and how this information impacts the clinical interpretation of urine culture results. 
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spelling doaj-art-0d03e191fb8a4a64984eea878b3e4bab2025-08-20T03:48:58ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802011-02-0150410.3855/jidc.923Antibiotic screening of urine culture as a useful quality auditGodwin Wilson0Shaherudeen Badarudeen1Angela Godwin2Laboratory Medicine and Pathology-Al Khor, Hamad Medical Corporation, Doha, QatarLaboratory Medicine and Pathology-Al Khor, Hamad Medical Corporation, Doha, QatarLaboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar Introduction: The diagnosis of urinary tract infections includes microbiologic culture of urine to determine the etiology of the infection. However, interpretation of the results can be confounded by various factors including the accuracy of a patient's history of current antibiotic usage.  Methodology: In this report, we tested urine specimens for the presence of antibiotics and compared our results to the accuracy of antibiotic data entry on the accompanying request forms. In addition, the consequences of culturing urine specimens with incomplete antibiotic history received in the laboratory were investigated. Results: During the study period, 14,680 urines were obtained and tested with a modified urine antibacterial substance assay (UABA). There were (97.32%) true-negative, 6 (0.04%) false-negative, 222 (1.51%) true-positive and 166 (1.13%) false-positive results. The sensitivity and specificity of this test was 97.37% and 98.85% respectively. Conclusion: This internal audit practice demonstrates the importance of accurately completed request forms and how this information impacts the clinical interpretation of urine culture results.  https://jidc.org/index.php/journal/article/view/923Urine antibiotic assayDrug resistanceAntibiotic HistoryUrine culture
spellingShingle Godwin Wilson
Shaherudeen Badarudeen
Angela Godwin
Antibiotic screening of urine culture as a useful quality audit
Journal of Infection in Developing Countries
Urine antibiotic assay
Drug resistance
Antibiotic History
Urine culture
title Antibiotic screening of urine culture as a useful quality audit
title_full Antibiotic screening of urine culture as a useful quality audit
title_fullStr Antibiotic screening of urine culture as a useful quality audit
title_full_unstemmed Antibiotic screening of urine culture as a useful quality audit
title_short Antibiotic screening of urine culture as a useful quality audit
title_sort antibiotic screening of urine culture as a useful quality audit
topic Urine antibiotic assay
Drug resistance
Antibiotic History
Urine culture
url https://jidc.org/index.php/journal/article/view/923
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