Characterization of drug susceptibility of Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection

The paper characterizes drug susceptibility in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection. The investigators have studied the spectrum of drug resistance in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with and wi...

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Main Authors: G. V. Panov, S. N. Skornyakov, A. I. Tsvetkov, E. E. Larionova, L. N. Chernousova
Format: Article
Language:Russian
Published: New Terra Publishing House 2015-02-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/341
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author G. V. Panov
S. N. Skornyakov
A. I. Tsvetkov
E. E. Larionova
L. N. Chernousova
author_facet G. V. Panov
S. N. Skornyakov
A. I. Tsvetkov
E. E. Larionova
L. N. Chernousova
author_sort G. V. Panov
collection DOAJ
description The paper characterizes drug susceptibility in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection. The investigators have studied the spectrum of drug resistance in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with and without HIV infection (172 and 309 clinical isolates, respectively). There are differences in the rate of primary drug resistance to antituberculosis drugs in patients with and without HIV infection (59 and 43.5% of the cases, respectively). The HIV-infected have also shown high rifampicin resistance rates in Mycobacterium tuberculosis (41.7%). The reasons for these differences are as yet unknown and call for further investigation.
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institution DOAJ
issn 2075-1230
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language Russian
publishDate 2015-02-01
publisher New Terra Publishing House
record_format Article
series Туберкулез и болезни лёгких
spelling doaj-art-0d01c94d76374cfd8c9d5fa8166295bf2025-08-20T03:02:32ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062015-02-0102505410.21292/2075-1230-2015-0-2-50-54341Characterization of drug susceptibility of Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infectionG. V. Panov0S. N. Skornyakov1A. I. Tsvetkov2E. E. Larionova3L. N. Chernousova4ГБУЗ СО «Противотуберкулезный диспансер»ФГБУ «Уральский научно-исследовательский институт фтизиопульмонологии» Министерства здравоохранения РФ, г. ЕкатеринбургГБУЗ СО «Противотуберкулезный диспансер»ФГБУ «Центральный научно-исследовательский институт туберкулеза» РАМН, г. МоскваФГБУ «Центральный научно-исследовательский институт туберкулеза» РАМН, г. МоскваThe paper characterizes drug susceptibility in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection. The investigators have studied the spectrum of drug resistance in Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with and without HIV infection (172 and 309 clinical isolates, respectively). There are differences in the rate of primary drug resistance to antituberculosis drugs in patients with and without HIV infection (59 and 43.5% of the cases, respectively). The HIV-infected have also shown high rifampicin resistance rates in Mycobacterium tuberculosis (41.7%). The reasons for these differences are as yet unknown and call for further investigation.https://www.tibl-journal.com/jour/article/view/341tuberculosis (tb)hiv/tbdrug resistance in mycobacterium tuberculosis
spellingShingle G. V. Panov
S. N. Skornyakov
A. I. Tsvetkov
E. E. Larionova
L. N. Chernousova
Characterization of drug susceptibility of Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection
Туберкулез и болезни лёгких
tuberculosis (tb)
hiv/tb
drug resistance in mycobacterium tuberculosis
title Characterization of drug susceptibility of Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection
title_full Characterization of drug susceptibility of Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection
title_fullStr Characterization of drug susceptibility of Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection
title_full_unstemmed Characterization of drug susceptibility of Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection
title_short Characterization of drug susceptibility of Mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with HIV infection
title_sort characterization of drug susceptibility of mycobacterium tuberculosis isolated from new cases of tuberculosis concurrent with hiv infection
topic tuberculosis (tb)
hiv/tb
drug resistance in mycobacterium tuberculosis
url https://www.tibl-journal.com/jour/article/view/341
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