The Potential Benefits of Curcumin-Enriched Diets for Adults with Colorectal Cancer: A Systematic Review
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. Conventional treatments such as chemotherapy and radiotherapy are often associated with severe side effects and limited effectiveness. Curcumin, a polyphenol derived from <i>Curcuma longa</i>, has dem...
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| Format: | Article |
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MDPI AG
2025-03-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/14/4/388 |
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| author | María Neira Constanza Mena Keila Torres Layla Simón |
| author_facet | María Neira Constanza Mena Keila Torres Layla Simón |
| author_sort | María Neira |
| collection | DOAJ |
| description | Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. Conventional treatments such as chemotherapy and radiotherapy are often associated with severe side effects and limited effectiveness. Curcumin, a polyphenol derived from <i>Curcuma longa</i>, has demonstrated anti-inflammatory and anticancer properties. A systematic review of the recent scientific literature followed PRISMA guidelines to evaluate the benefits of a curcumin-enriched diet for adults with colorectal cancer. Articles published between 2018 and 2024 were retrieved from PubMed, SciELO, Google Scholar, and Scopus. Studies meeting the inclusion criteria focused on curcumin, adults, and colorectal cancer outcomes. The administration of curcumin-containing products was associated with improved survival rates, enhanced quality of life, tumor reduction, and anti-inflammatory effects. A curcumin-enriched diet shows potential as an effective adjunct therapy for CRC patients, though its limited bioavailability and potential side effects, such as gastrointestinal discomfort, pose challenges. Addressing these limitations through larger cohorts, extended study durations, and improved formulations to enhance bioavailability is essential. Such efforts could enable the development of personalized dietary recommendations for CRC management. |
| format | Article |
| id | doaj-art-0cffc8e1140c4336ba3d362eccf87bdb |
| institution | OA Journals |
| issn | 2076-3921 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj-art-0cffc8e1140c4336ba3d362eccf87bdb2025-08-20T02:17:19ZengMDPI AGAntioxidants2076-39212025-03-0114438810.3390/antiox14040388The Potential Benefits of Curcumin-Enriched Diets for Adults with Colorectal Cancer: A Systematic ReviewMaría Neira0Constanza Mena1Keila Torres2Layla Simón3Escuela de Nutrición y Dietética, Universidad Finis Terrae, Santiago 7501015, ChileEscuela de Nutrición y Dietética, Universidad Finis Terrae, Santiago 7501015, ChileEscuela de Nutrición y Dietética, Universidad Finis Terrae, Santiago 7501015, ChileEscuela de Nutrición y Dietética, Universidad Finis Terrae, Santiago 7501015, ChileColorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. Conventional treatments such as chemotherapy and radiotherapy are often associated with severe side effects and limited effectiveness. Curcumin, a polyphenol derived from <i>Curcuma longa</i>, has demonstrated anti-inflammatory and anticancer properties. A systematic review of the recent scientific literature followed PRISMA guidelines to evaluate the benefits of a curcumin-enriched diet for adults with colorectal cancer. Articles published between 2018 and 2024 were retrieved from PubMed, SciELO, Google Scholar, and Scopus. Studies meeting the inclusion criteria focused on curcumin, adults, and colorectal cancer outcomes. The administration of curcumin-containing products was associated with improved survival rates, enhanced quality of life, tumor reduction, and anti-inflammatory effects. A curcumin-enriched diet shows potential as an effective adjunct therapy for CRC patients, though its limited bioavailability and potential side effects, such as gastrointestinal discomfort, pose challenges. Addressing these limitations through larger cohorts, extended study durations, and improved formulations to enhance bioavailability is essential. Such efforts could enable the development of personalized dietary recommendations for CRC management.https://www.mdpi.com/2076-3921/14/4/388<i>Curcuma</i>colorectal adenomaanticancer dietsanti-inflammatory agentsantioxidantsgastrointestinal health |
| spellingShingle | María Neira Constanza Mena Keila Torres Layla Simón The Potential Benefits of Curcumin-Enriched Diets for Adults with Colorectal Cancer: A Systematic Review Antioxidants <i>Curcuma</i> colorectal adenoma anticancer diets anti-inflammatory agents antioxidants gastrointestinal health |
| title | The Potential Benefits of Curcumin-Enriched Diets for Adults with Colorectal Cancer: A Systematic Review |
| title_full | The Potential Benefits of Curcumin-Enriched Diets for Adults with Colorectal Cancer: A Systematic Review |
| title_fullStr | The Potential Benefits of Curcumin-Enriched Diets for Adults with Colorectal Cancer: A Systematic Review |
| title_full_unstemmed | The Potential Benefits of Curcumin-Enriched Diets for Adults with Colorectal Cancer: A Systematic Review |
| title_short | The Potential Benefits of Curcumin-Enriched Diets for Adults with Colorectal Cancer: A Systematic Review |
| title_sort | potential benefits of curcumin enriched diets for adults with colorectal cancer a systematic review |
| topic | <i>Curcuma</i> colorectal adenoma anticancer diets anti-inflammatory agents antioxidants gastrointestinal health |
| url | https://www.mdpi.com/2076-3921/14/4/388 |
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