Real-world analysis of strategies to prevent thrombosis and bleeding in adults with ALL treated with asparaginase

Real-world analysis of strategies to prevent thrombosis and bleeding in adults with ALL treated with asparaginase

Abstract: The prognosis of adult patients with acute lymphoblastic leukemia (ALL) has improved with the incorporation of pediatric-inspired regimens that contain PEGylated asparaginase (PEG-Asp). However, PEG-Asp administration is associated with an increased rate of thrombosis. Data regarding the b...

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Main Authors: Joseph F. Mort, David Brighton, Benjamin Mautner, Eric Pierce, Farid Ghamsari, Cecily Allen, Darren D’Souza, Imari Patel, Justin Lawson, Clayton Jackson, Karin Abernathy, Bradley Yelvington, Ryan Miller, Bhagirathbhai Dholaria, Heather Wolfe, Jordan Infield, Susan C. Locke, Rory M. Shallis, Vu H. Duong, Daniel R. Reed, Katherine Walsh, Thomas W. LeBlanc, Michael Keng, Bethany Horton, Firas El Chaer
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Vessels, Thrombosis & Hemostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2950327225000221
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