Single-cell analysis identified key macrophage subpopulations associated with atherosclerosis
Atherosclerosis is a lipid-driven inflammatory disease characterized by plaque formation in major arteries. These plaques contain lipid-rich macrophages that accumulate through monocyte recruitment, local macrophage differentiation, and proliferation.
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2024-12-01
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| Series: | Open Medicine |
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| Online Access: | https://doi.org/10.1515/med-2024-1088 |
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| _version_ | 1823860473529892864 |
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| author | Zhao Zhenzhen Qin Yuelong Wu Rui Li Wenwu Dong Yujiang |
| author_facet | Zhao Zhenzhen Qin Yuelong Wu Rui Li Wenwu Dong Yujiang |
| author_sort | Zhao Zhenzhen |
| collection | DOAJ |
| description | Atherosclerosis is a lipid-driven inflammatory disease characterized by plaque formation in major arteries. These plaques contain lipid-rich macrophages that accumulate through monocyte recruitment, local macrophage differentiation, and proliferation. |
| format | Article |
| id | doaj-art-0cf05e85d7f549ed86dbbbb788ed0227 |
| institution | Kabale University |
| issn | 2391-5463 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj-art-0cf05e85d7f549ed86dbbbb788ed02272025-02-10T13:24:39ZengDe GruyterOpen Medicine2391-54632024-12-011911516010.1515/med-2024-1088Single-cell analysis identified key macrophage subpopulations associated with atherosclerosisZhao Zhenzhen0Qin Yuelong1Wu Rui2Li Wenwu3Dong Yujiang4First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, 250000, ChinaFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, 250000, ChinaPingyi County Hospital of Traditional Chinese Medicine Cardiology Department, Linyi, 273300, ChinaDepartment of Burn Plastic and Wound Repair Surgery, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, ChinaShandong University of Traditional Chinese Medicine, Jinan, 250014, ChinaAtherosclerosis is a lipid-driven inflammatory disease characterized by plaque formation in major arteries. These plaques contain lipid-rich macrophages that accumulate through monocyte recruitment, local macrophage differentiation, and proliferation.https://doi.org/10.1515/med-2024-1088atherosclerosismacrophageclinical outcomefcn1ccl |
| spellingShingle | Zhao Zhenzhen Qin Yuelong Wu Rui Li Wenwu Dong Yujiang Single-cell analysis identified key macrophage subpopulations associated with atherosclerosis Open Medicine atherosclerosis macrophage clinical outcome fcn1 ccl |
| title | Single-cell analysis identified key macrophage subpopulations associated with atherosclerosis |
| title_full | Single-cell analysis identified key macrophage subpopulations associated with atherosclerosis |
| title_fullStr | Single-cell analysis identified key macrophage subpopulations associated with atherosclerosis |
| title_full_unstemmed | Single-cell analysis identified key macrophage subpopulations associated with atherosclerosis |
| title_short | Single-cell analysis identified key macrophage subpopulations associated with atherosclerosis |
| title_sort | single cell analysis identified key macrophage subpopulations associated with atherosclerosis |
| topic | atherosclerosis macrophage clinical outcome fcn1 ccl |
| url | https://doi.org/10.1515/med-2024-1088 |
| work_keys_str_mv | AT zhaozhenzhen singlecellanalysisidentifiedkeymacrophagesubpopulationsassociatedwithatherosclerosis AT qinyuelong singlecellanalysisidentifiedkeymacrophagesubpopulationsassociatedwithatherosclerosis AT wurui singlecellanalysisidentifiedkeymacrophagesubpopulationsassociatedwithatherosclerosis AT liwenwu singlecellanalysisidentifiedkeymacrophagesubpopulationsassociatedwithatherosclerosis AT dongyujiang singlecellanalysisidentifiedkeymacrophagesubpopulationsassociatedwithatherosclerosis |