Senescent alveolar type II epithelial cells-secreted GDF15 promotes silicosis progression via interfering intercellular communication

Senescent alveolar type II epithelial cells-secreted GDF15 promotes silicosis progression via interfering intercellular communication

Background: Silicosis is a chronic fibrotic pulmonary disease caused by consistent inhalation of respirable crystalline-free silica dust. The senescence of alveolar epithelial type II cells (ATII) is considered the initiation of pulmonary fibrosis. As a secreted protein, growth differentiation facto...

Full description

Saved in:
Bibliographic Details
Main Authors: Wenxiu Lian, Demin Cheng, Wenqing Sun, Ting Wang, Xinying Jia, Zhenhua Jia, Yi Liu, Chunhui Ni
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
silicosis
ATII cell
senescence
GDF15
cellular microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325002532
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items