Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies
Background. Physical exercise (PE) has been associated with increase neuroplasticity, neurotrophic factors, and improvements in brain function. Objective. To evaluate the effects of different PE protocols on neuroplasticity components and brain function in a human and animal model. Methods. We condu...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2020/8856621 |
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| author | Matheus Santos de Sousa Fernandes Tayrine Figueira Ordônio Gabriela Carvalho Jurema Santos Lucas Eduardo R. Santos Camila Tenório Calazans Dayane Aparecida Gomes Tony Meireles Santos |
| author_facet | Matheus Santos de Sousa Fernandes Tayrine Figueira Ordônio Gabriela Carvalho Jurema Santos Lucas Eduardo R. Santos Camila Tenório Calazans Dayane Aparecida Gomes Tony Meireles Santos |
| author_sort | Matheus Santos de Sousa Fernandes |
| collection | DOAJ |
| description | Background. Physical exercise (PE) has been associated with increase neuroplasticity, neurotrophic factors, and improvements in brain function. Objective. To evaluate the effects of different PE protocols on neuroplasticity components and brain function in a human and animal model. Methods. We conducted a systematic review process from November 2019 to January 2020 of the following databases: PubMed, ScienceDirect, SciELO, LILACS, and Scopus. A keyword combination referring to PE and neuroplasticity was included as part of a more thorough search process. From an initial number of 20,782 original articles, after reading the titles and abstracts, twenty-one original articles were included. Two investigators evaluated the abstract, the data of the study, the design, the sample size, the participant characteristics, and the PE protocol. Results. PE increases neuroplasticity via neurotrophic factors (BDNF, GDNF, and NGF) and receptor (TrkB and P75NTR) production providing improvements in neuroplasticity, and cognitive function (learning and memory) in human and animal models. Conclusion. PE was effective for increasing the production of neurotrophic factors, cell growth, and proliferation, as well as for improving brain functionality. |
| format | Article |
| id | doaj-art-0ce15089854c4b32bf9fc505513d9efa |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-0ce15089854c4b32bf9fc505513d9efa2025-02-03T01:04:25ZengWileyNeural Plasticity2090-59041687-54432020-01-01202010.1155/2020/88566218856621Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal StudiesMatheus Santos de Sousa Fernandes0Tayrine Figueira Ordônio1Gabriela Carvalho Jurema Santos2Lucas Eduardo R. Santos3Camila Tenório Calazans4Dayane Aparecida Gomes5Tony Meireles Santos6Neuropsquiatry and Behavior Science Postgraduate Program, Federal University of Pernambuco, Recife, PE, BrazilLaboratório de Imunopatologia Keizo Asami-LIKA, University of Pernambuco, Recife, PE, BrazilAcademic Center of Vitoria de Santo Antão, Federal University of Pernambuco, PE, BrazilNeuropsquiatry and Behavior Science Postgraduate Program, Federal University of Pernambuco, Recife, PE, BrazilSchool of Physical Education, University of Pernambuco, Recife, PE, BrazilNeuropsquiatry and Behavior Science Postgraduate Program, Federal University of Pernambuco, Recife, PE, BrazilNeuropsquiatry and Behavior Science Postgraduate Program, Federal University of Pernambuco, Recife, PE, BrazilBackground. Physical exercise (PE) has been associated with increase neuroplasticity, neurotrophic factors, and improvements in brain function. Objective. To evaluate the effects of different PE protocols on neuroplasticity components and brain function in a human and animal model. Methods. We conducted a systematic review process from November 2019 to January 2020 of the following databases: PubMed, ScienceDirect, SciELO, LILACS, and Scopus. A keyword combination referring to PE and neuroplasticity was included as part of a more thorough search process. From an initial number of 20,782 original articles, after reading the titles and abstracts, twenty-one original articles were included. Two investigators evaluated the abstract, the data of the study, the design, the sample size, the participant characteristics, and the PE protocol. Results. PE increases neuroplasticity via neurotrophic factors (BDNF, GDNF, and NGF) and receptor (TrkB and P75NTR) production providing improvements in neuroplasticity, and cognitive function (learning and memory) in human and animal models. Conclusion. PE was effective for increasing the production of neurotrophic factors, cell growth, and proliferation, as well as for improving brain functionality.http://dx.doi.org/10.1155/2020/8856621 |
| spellingShingle | Matheus Santos de Sousa Fernandes Tayrine Figueira Ordônio Gabriela Carvalho Jurema Santos Lucas Eduardo R. Santos Camila Tenório Calazans Dayane Aparecida Gomes Tony Meireles Santos Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies Neural Plasticity |
| title | Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies |
| title_full | Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies |
| title_fullStr | Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies |
| title_full_unstemmed | Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies |
| title_short | Effects of Physical Exercise on Neuroplasticity and Brain Function: A Systematic Review in Human and Animal Studies |
| title_sort | effects of physical exercise on neuroplasticity and brain function a systematic review in human and animal studies |
| url | http://dx.doi.org/10.1155/2020/8856621 |
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