DEmiRNA-mRNA regulatory network reveals miR‐122-5p as a regulatory factor of arginine metabolism in necrotizing enterocolitis

DEmiRNA-mRNA regulatory network reveals miR‐122-5p as a regulatory factor of arginine metabolism in necrotizing enterocolitis

ObjectiveNecrotizing enterocolitis (NEC) is a gastrointestinal emergency with relatively high morbidity and mortality in neonates. The role of microRNAs (miRNAs) in NEC is not yet entirely clear. This study aimed to explore the mechanism of miR-122-5p in NEC.MethodsDifferentially expressed (DE) miRN...

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Bibliographic Details
Main Authors: Zhili Ding, Ting Guo, Qiang Tang, Yaqiang Hong, Zhibao Lv, Li Lu, Wenjun Zhuang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Genetics
Subjects:
neonatal necrotizing enterocolitis
miR-122-5p
arginine metabolism
intestinal stem cell
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1480431/full
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