Nitric Oxide Regulates Multiple Signal Pathways in Plants via Protein <i>S</i>-Nitrosylation
Nitric oxide (NO) can perform its physiological role through protein <i>S</i>-nitrosylation, a redox-based post-translational modification (PTM). This review details the specific molecular mechanisms and current detection technologies of <i>S</i>-nitrosylation. It also compre...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-05-01
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| Series: | Current Issues in Molecular Biology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1467-3045/47/6/407 |
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| Summary: | Nitric oxide (NO) can perform its physiological role through protein <i>S</i>-nitrosylation, a redox-based post-translational modification (PTM). This review details the specific molecular mechanisms and current detection technologies of <i>S</i>-nitrosylation. It also comprehensively synthesizes emerging evidence of <i>S</i>-nitrosylation roles in plant biological processes, including growth and development, immune signaling, stress responses and symbiotic nitrogen fixation. Furthermore, the review analyzes research progress on the crosstalk between <i>S</i>-nitrosylation and other protein PTMs. Finally, unresolved issues such as the spatio-temporal resolution of SNO-proteome mapping and standardized protocols for reproducibility are pointed out. In summary, this work proposes a roadmap for future research. |
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| ISSN: | 1467-3037 1467-3045 |