Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons

Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons

Abstract Lysosomes are membrane-bound organelles critical for maintaining cellular homeostasis. Delivery of biosynthetic lysosomal proteins to lysosomes is crucial to orchestrate proper lysosomal function. However, it remains unknown how the delivery of biosynthetic lysosomal proteins to lysosomes i...

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Bibliographic Details
Main Authors: Chun Hei Li, Noortje Kersten, Nazmiye Özkan, Dan T. M. Nguyen, Max Koppers, Harm Post, Maarten Altelaar, Ginny G. Farias
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55052-w
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