Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizations

Abstract Background Although the number of Dutch guidelines is growing, their uptake and impact in clinical practice lag behind. Dutch guideline organizations, including guideline developers, governmental agencies, health insurers and other national organizations, play a crucial role in developing,...

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Main Authors: Andrea C. Thoonsen, Anika Gans, Toby T. Broeders, Ilse van Beusekom, Diana M. J. Delnoij, Martine C. de Bruijne, Hanneke Merten
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Health Services Research
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Online Access:https://doi.org/10.1186/s12913-025-12270-2
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author Andrea C. Thoonsen
Anika Gans
Toby T. Broeders
Ilse van Beusekom
Diana M. J. Delnoij
Martine C. de Bruijne
Hanneke Merten
author_facet Andrea C. Thoonsen
Anika Gans
Toby T. Broeders
Ilse van Beusekom
Diana M. J. Delnoij
Martine C. de Bruijne
Hanneke Merten
author_sort Andrea C. Thoonsen
collection DOAJ
description Abstract Background Although the number of Dutch guidelines is growing, their uptake and impact in clinical practice lag behind. Dutch guideline organizations, including guideline developers, governmental agencies, health insurers and other national organizations, play a crucial role in developing, authorizing and/or supporting the use of guidelines. They influence end users' awareness, accessibility, understanding, acceptability and applicability of guidelines. In this study, we explored the barriers and facilitators that representatives of guideline organizations perceive in nationwide guideline implementation. Methods In this qualitative study, we conducted semi-structured interviews with 35 representatives of 24 different guideline organizations. We employed framework analysis, using the updated Consolidated Framework for Implementation Research (CFIR), and thematic analysis to guide our data analysis and synthesis. Results We found 45 different implementation barriers and 35 implementation facilitators. We identified seven overarching themes of interrelated barriers and facilitators that extended across the stakeholders involved and domains within the updated CFIR. These included 1) healthcare demand and resource availability, 2) implementation knowledge and expertise, 3) guideline characteristics: representation, evidence base and design, 4) partnerships and collaboration, 5) characteristics of guideline implementation planning, execution and evaluation strategies, 6) characteristics of healthcare professionals: need, capability, opportunity and motivation, and 7) legal and regulatory compliance. Conclusions We obtained valuable insights into the complex dynamics of barriers and facilitators perceived by guideline organizations in nationwide guideline implementation. Our findings help explain why healthcare professionals and healthcare facilities may (not), slowly or inconsistently adhere to guideline recommendations in practice. The identified barriers and facilitators provide guidance for policymakers to re-evaluate and improve nationwide quality and guideline implementation policies, to eventually improve clinical practice and health outcomes for patients.
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spelling doaj-art-0cc468db53614c0b9a373826a27de5412025-02-02T12:14:35ZengBMCBMC Health Services Research1472-69632025-01-0125111810.1186/s12913-025-12270-2Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizationsAndrea C. Thoonsen0Anika Gans1Toby T. Broeders2Ilse van Beusekom3Diana M. J. Delnoij4Martine C. de Bruijne5Hanneke Merten6Amsterdam UMC, Department of Public and Occupational Health, Vrije Universiteit Amsterdam, Amsterdam Public Health research instituteAmsterdam UMC, Department of Public and Occupational Health, Vrije Universiteit Amsterdam, Amsterdam Public Health research instituteAmsterdam UMC, Department of Public and Occupational Health, Vrije Universiteit Amsterdam, Amsterdam Public Health research instituteZorginstituut Nederland, Department of CareZorginstituut Nederland, Department of CareAmsterdam UMC, Department of Public and Occupational Health, Vrije Universiteit Amsterdam, Amsterdam Public Health research instituteAmsterdam UMC, Department of Public and Occupational Health, Vrije Universiteit Amsterdam, Amsterdam Public Health research instituteAbstract Background Although the number of Dutch guidelines is growing, their uptake and impact in clinical practice lag behind. Dutch guideline organizations, including guideline developers, governmental agencies, health insurers and other national organizations, play a crucial role in developing, authorizing and/or supporting the use of guidelines. They influence end users' awareness, accessibility, understanding, acceptability and applicability of guidelines. In this study, we explored the barriers and facilitators that representatives of guideline organizations perceive in nationwide guideline implementation. Methods In this qualitative study, we conducted semi-structured interviews with 35 representatives of 24 different guideline organizations. We employed framework analysis, using the updated Consolidated Framework for Implementation Research (CFIR), and thematic analysis to guide our data analysis and synthesis. Results We found 45 different implementation barriers and 35 implementation facilitators. We identified seven overarching themes of interrelated barriers and facilitators that extended across the stakeholders involved and domains within the updated CFIR. These included 1) healthcare demand and resource availability, 2) implementation knowledge and expertise, 3) guideline characteristics: representation, evidence base and design, 4) partnerships and collaboration, 5) characteristics of guideline implementation planning, execution and evaluation strategies, 6) characteristics of healthcare professionals: need, capability, opportunity and motivation, and 7) legal and regulatory compliance. Conclusions We obtained valuable insights into the complex dynamics of barriers and facilitators perceived by guideline organizations in nationwide guideline implementation. Our findings help explain why healthcare professionals and healthcare facilities may (not), slowly or inconsistently adhere to guideline recommendations in practice. The identified barriers and facilitators provide guidance for policymakers to re-evaluate and improve nationwide quality and guideline implementation policies, to eventually improve clinical practice and health outcomes for patients.https://doi.org/10.1186/s12913-025-12270-2Clinical practice guidelinesGuideline adherenceImplementation scienceGuideline organizationsQuality improvementBarriers and facilitators
spellingShingle Andrea C. Thoonsen
Anika Gans
Toby T. Broeders
Ilse van Beusekom
Diana M. J. Delnoij
Martine C. de Bruijne
Hanneke Merten
Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizations
BMC Health Services Research
Clinical practice guidelines
Guideline adherence
Implementation science
Guideline organizations
Quality improvement
Barriers and facilitators
title Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizations
title_full Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizations
title_fullStr Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizations
title_full_unstemmed Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizations
title_short Nationwide guideline implementation: a qualitative study of barriers and facilitators from the perspective of guideline organizations
title_sort nationwide guideline implementation a qualitative study of barriers and facilitators from the perspective of guideline organizations
topic Clinical practice guidelines
Guideline adherence
Implementation science
Guideline organizations
Quality improvement
Barriers and facilitators
url https://doi.org/10.1186/s12913-025-12270-2
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