Case Report: Anti-platelet factor 4 -mediated immunothrombosis in a patient with ANCA vasculitis – a shared mechanism of NETosis

Case Report: Anti-platelet factor 4 -mediated immunothrombosis in a patient with ANCA vasculitis – a shared mechanism of NETosis

Anti-platelet factor 4 (PF4) immunothrombosis is characterized by thrombocytopenia, thrombosis and enhanced NETosis and has been described in the absence of prior heparin exposure. This case report describes a patient with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) who, w...

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Bibliographic Details
Main Authors: Lital Remez-Gabay, Olga Vdovich, Luiza Akria, Etty Kruzel-Davila
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
anti-PF4 immunothrombosis
NEtosis
ANCA
IVIg
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567999/full
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