Efficiency analysis of nutritional screening tools for children with congenital heart disease: a retrospective observational study
ObjectiveThis study aims to (1) determine the prevalence of malnutrition among hospitalized children with congenital heart disease (CHD), (2) evaluate the effectiveness of common pediatric nutritional screening tools across various age groups, and (3) specifically assess the tools’ efficacy in ident...
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Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2025.1572805/full |
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| author | Ying Xu Yingying Jiang Minzhi Guo Yiping Wang Hongmiao Huang Jiaqian Xie Dongshan Liao Dongshan Liao |
| author_facet | Ying Xu Yingying Jiang Minzhi Guo Yiping Wang Hongmiao Huang Jiaqian Xie Dongshan Liao Dongshan Liao |
| author_sort | Ying Xu |
| collection | DOAJ |
| description | ObjectiveThis study aims to (1) determine the prevalence of malnutrition among hospitalized children with congenital heart disease (CHD), (2) evaluate the effectiveness of common pediatric nutritional screening tools across various age groups, and (3) specifically assess the tools’ efficacy in identifying severe malnutrition, thereby facilitating early nutritional intervention.MethodsA retrospective observational analysis was performed using clinical data from 3,677 children (0–18 years) with congenital heart disease who underwent surgical intervention at the Cardiothoracic Surgery Center between January 2018 and December 2022. The World Health Organization growth curves were used as standards to compare the efficacy of four screening tools: Screening Tool for the Assessment of Malnutrition in Pediatrics (STAMP), Screening Tool Risk on Nutritional status and Growth (STRONGkids), Risk Adjustment in Congenital Heart Surgery-1 method (RACHS-1), and the combined STAMP + STRONGkids (SS) adjusted score across different age groups. Categorical data were expressed as percentages, and Chi-square tests were used for statistical analysis, with pairwise comparisons performed using Bonferroni correction. Receiver Operating Characteristic (ROC) curves were employed to calculate specificity, sensitivity, and optimal cutoff values. The consistency of screening results was further assessed using Youden’s index and Kappa values.ResultsThe prevalence of malnutrition among CHD patients was 32.9% (1,208/3,667). Using World Health Organization (WHO) curves as the gold standard for diagnosing malnutrition, the AUC for the ROC curves of STAMP, STRONGkids, and SS were 0.841, 0.747, and 0.863 (P < 0.01), respectively, for nutritional risk screening among CHD patients. Optimal Youden indices were achieved at a STAMP score of 3.5 (55.9%), a STRONGkids score of 2.5 (41.5%), and an SS score of 3.25 (64.5%). Age-based subgroup analysis revealed that STAMP had the best sensitivity of 70.1% (Negative Prediction Rate (NPV) 96.1) at a score of 3.5 for children aged 6–18 years, STRONGkids showed optimal sensitivity of 78.1% (NPV 77.3) at a score of 2.5 for infants aged 0–1 year, and SS demonstrated 74.7% sensitivity (NPV 96.6) at a score of 3.25 for children aged 6–18 years. Further analysis indicated that STAMP at a score of 2.5 and SS at a score of 2.75 showed balanced sensitivity and specificity across all age groups. Additionally, for different degrees of nutritional deficiencies, STAMP at 3.5 and SS at 3.25 demonstrated ideal specificity, with all Kappa values being P < 0.001.ConclusionFor hospitalized CHD patients aged 0–18 years, the nutritional screening tool STAMP is more effective than STRONGkids, and SS combines the advantages of both tools as it demonstrates the best screening efficacy. However, the area under the ROC curve (AUC) for the RACHS-1 score was 0.525 (P >0.01), indicating not suitable for nutritional risk screening. To enhance sensitivity in screening malnutrition in CHD patients, the recommended cutoff values are 3 for STAMP and 2.5 for SS. For identifying severe malnutrition, STAMP at a cutoff of 3.5 and SS at 3.25 show higher overall screening efficacy. |
| format | Article |
| id | doaj-art-0cc0597838ea4422b9d5d6d8dc263f03 |
| institution | Kabale University |
| issn | 2296-861X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj-art-0cc0597838ea4422b9d5d6d8dc263f032025-08-20T03:29:15ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-06-011210.3389/fnut.2025.15728051572805Efficiency analysis of nutritional screening tools for children with congenital heart disease: a retrospective observational studyYing Xu0Yingying Jiang1Minzhi Guo2Yiping Wang3Hongmiao Huang4Jiaqian Xie5Dongshan Liao6Dongshan Liao7Department of Clinical Nutrition, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Occupational Health, Fujian Center for Prevention and Control of Occupational Diseases and Chemical poisoning, Fuzhou, ChinaDepartment of Clinical Nutrition, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Clinical Nutrition, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Food and Nutritional Sciences, University of Ottawa, Ottawa, ON, CanadaDepartment of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaFujian Provincial Center for Cardiovascular Medicine, Fuzhou, ChinaObjectiveThis study aims to (1) determine the prevalence of malnutrition among hospitalized children with congenital heart disease (CHD), (2) evaluate the effectiveness of common pediatric nutritional screening tools across various age groups, and (3) specifically assess the tools’ efficacy in identifying severe malnutrition, thereby facilitating early nutritional intervention.MethodsA retrospective observational analysis was performed using clinical data from 3,677 children (0–18 years) with congenital heart disease who underwent surgical intervention at the Cardiothoracic Surgery Center between January 2018 and December 2022. The World Health Organization growth curves were used as standards to compare the efficacy of four screening tools: Screening Tool for the Assessment of Malnutrition in Pediatrics (STAMP), Screening Tool Risk on Nutritional status and Growth (STRONGkids), Risk Adjustment in Congenital Heart Surgery-1 method (RACHS-1), and the combined STAMP + STRONGkids (SS) adjusted score across different age groups. Categorical data were expressed as percentages, and Chi-square tests were used for statistical analysis, with pairwise comparisons performed using Bonferroni correction. Receiver Operating Characteristic (ROC) curves were employed to calculate specificity, sensitivity, and optimal cutoff values. The consistency of screening results was further assessed using Youden’s index and Kappa values.ResultsThe prevalence of malnutrition among CHD patients was 32.9% (1,208/3,667). Using World Health Organization (WHO) curves as the gold standard for diagnosing malnutrition, the AUC for the ROC curves of STAMP, STRONGkids, and SS were 0.841, 0.747, and 0.863 (P < 0.01), respectively, for nutritional risk screening among CHD patients. Optimal Youden indices were achieved at a STAMP score of 3.5 (55.9%), a STRONGkids score of 2.5 (41.5%), and an SS score of 3.25 (64.5%). Age-based subgroup analysis revealed that STAMP had the best sensitivity of 70.1% (Negative Prediction Rate (NPV) 96.1) at a score of 3.5 for children aged 6–18 years, STRONGkids showed optimal sensitivity of 78.1% (NPV 77.3) at a score of 2.5 for infants aged 0–1 year, and SS demonstrated 74.7% sensitivity (NPV 96.6) at a score of 3.25 for children aged 6–18 years. Further analysis indicated that STAMP at a score of 2.5 and SS at a score of 2.75 showed balanced sensitivity and specificity across all age groups. Additionally, for different degrees of nutritional deficiencies, STAMP at 3.5 and SS at 3.25 demonstrated ideal specificity, with all Kappa values being P < 0.001.ConclusionFor hospitalized CHD patients aged 0–18 years, the nutritional screening tool STAMP is more effective than STRONGkids, and SS combines the advantages of both tools as it demonstrates the best screening efficacy. However, the area under the ROC curve (AUC) for the RACHS-1 score was 0.525 (P >0.01), indicating not suitable for nutritional risk screening. To enhance sensitivity in screening malnutrition in CHD patients, the recommended cutoff values are 3 for STAMP and 2.5 for SS. For identifying severe malnutrition, STAMP at a cutoff of 3.5 and SS at 3.25 show higher overall screening efficacy.https://www.frontiersin.org/articles/10.3389/fnut.2025.1572805/fullcongenital heart diseasenutritional screeningmalnutritionSTAMPSTRONGkids |
| spellingShingle | Ying Xu Yingying Jiang Minzhi Guo Yiping Wang Hongmiao Huang Jiaqian Xie Dongshan Liao Dongshan Liao Efficiency analysis of nutritional screening tools for children with congenital heart disease: a retrospective observational study Frontiers in Nutrition congenital heart disease nutritional screening malnutrition STAMP STRONGkids |
| title | Efficiency analysis of nutritional screening tools for children with congenital heart disease: a retrospective observational study |
| title_full | Efficiency analysis of nutritional screening tools for children with congenital heart disease: a retrospective observational study |
| title_fullStr | Efficiency analysis of nutritional screening tools for children with congenital heart disease: a retrospective observational study |
| title_full_unstemmed | Efficiency analysis of nutritional screening tools for children with congenital heart disease: a retrospective observational study |
| title_short | Efficiency analysis of nutritional screening tools for children with congenital heart disease: a retrospective observational study |
| title_sort | efficiency analysis of nutritional screening tools for children with congenital heart disease a retrospective observational study |
| topic | congenital heart disease nutritional screening malnutrition STAMP STRONGkids |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2025.1572805/full |
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