Modern Trends in Imaging XI: Impedance Measurements in the Biomedical Sciences

Biological organisms and their component organs, tissues and cells have unique electrical impedance properties. Impedance properties often change with changes in structure, composition, and metabolism, and can be indicative of the onset and progression of disease states. Over the past 100 years, ins...

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Main Authors: Frederick D. Coffman, Stanley Cohen
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-2012-0070
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author Frederick D. Coffman
Stanley Cohen
author_facet Frederick D. Coffman
Stanley Cohen
author_sort Frederick D. Coffman
collection DOAJ
description Biological organisms and their component organs, tissues and cells have unique electrical impedance properties. Impedance properties often change with changes in structure, composition, and metabolism, and can be indicative of the onset and progression of disease states. Over the past 100 years, instruments and analytical methods have been developed to measure the impedance properties of biological specimens and to utilize these measurements in both clinical and basic science settings. This chapter will review the applications of impedance measurements in the biomedical sciences, from whole body analysis to impedance measurements of single cells and cell monolayers, and how cellular impedance measuring instruments can now be used in high throughput screening applications.
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spelling doaj-art-0cbff5765f614cbc81d55599a49ff05d2025-08-20T02:03:04ZengWileyAnalytical Cellular Pathology2210-71772210-71852012-01-01355-636337410.3233/ACP-2012-0070Modern Trends in Imaging XI: Impedance Measurements in the Biomedical SciencesFrederick D. Coffman0Stanley Cohen1Department of Pathology and Laboratory Medicine, UMDNJ–New Jersey Medical School, Newark, NJ, USACenter for Biophysical Pathology, UMDNJ–New Jersey Medical School, Newark, NJ, USABiological organisms and their component organs, tissues and cells have unique electrical impedance properties. Impedance properties often change with changes in structure, composition, and metabolism, and can be indicative of the onset and progression of disease states. Over the past 100 years, instruments and analytical methods have been developed to measure the impedance properties of biological specimens and to utilize these measurements in both clinical and basic science settings. This chapter will review the applications of impedance measurements in the biomedical sciences, from whole body analysis to impedance measurements of single cells and cell monolayers, and how cellular impedance measuring instruments can now be used in high throughput screening applications.http://dx.doi.org/10.3233/ACP-2012-0070
spellingShingle Frederick D. Coffman
Stanley Cohen
Modern Trends in Imaging XI: Impedance Measurements in the Biomedical Sciences
Analytical Cellular Pathology
title Modern Trends in Imaging XI: Impedance Measurements in the Biomedical Sciences
title_full Modern Trends in Imaging XI: Impedance Measurements in the Biomedical Sciences
title_fullStr Modern Trends in Imaging XI: Impedance Measurements in the Biomedical Sciences
title_full_unstemmed Modern Trends in Imaging XI: Impedance Measurements in the Biomedical Sciences
title_short Modern Trends in Imaging XI: Impedance Measurements in the Biomedical Sciences
title_sort modern trends in imaging xi impedance measurements in the biomedical sciences
url http://dx.doi.org/10.3233/ACP-2012-0070
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