Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study
Background The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frai...
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Korea Geriatrics Society
2025-03-01
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| Series: | Annals of Geriatric Medicine and Research |
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| Online Access: | http://www.e-agmr.org/upload/pdf/agmr-24-0144.pdf |
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| author | Siti Setiati Kuntjoro Harimurti Ika Fitriana Noto Dwimartutie Rahmi Istanti Muhammad Khifzhon Azwar I Gusti Putu Suka Aryana Sri Sunarti Agus Sudarso Dina Aprillia Ariestine Lazuardhi Dwipa Novira Widajanti Nur Riviati Roza Mulyana Rensa Rensa Yudo Murti Mupangati Fatichati Budiningsih Nina Kemala Sari |
| author_facet | Siti Setiati Kuntjoro Harimurti Ika Fitriana Noto Dwimartutie Rahmi Istanti Muhammad Khifzhon Azwar I Gusti Putu Suka Aryana Sri Sunarti Agus Sudarso Dina Aprillia Ariestine Lazuardhi Dwipa Novira Widajanti Nur Riviati Roza Mulyana Rensa Rensa Yudo Murti Mupangati Fatichati Budiningsih Nina Kemala Sari |
| author_sort | Siti Setiati |
| collection | DOAJ |
| description | Background The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap and the associated factors in community-dwelling older outpatients. Methods We collected data from community-dwelling outpatients aged ≥60 years in Indonesian geriatric care centres to conduct this cross-sectional study with bivariate and multivariable analyses. Frailty, possible sarcopenia, and malnutrition diagnoses were based on FRAIL scale, Asian Working Group for Sarcopenia 2019 consensus, and Mini Nutritional Assessment Short Form, respectively. Results The prevalence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients were 13.6%, 45.5%, and 5.3%, respectively. The prevalence of co-occurrence of frailty, possible sarcopenia and malnutrition was 3.3%. It was associated with transient ischemic attack (TIA) and cerebrovascular accident (odds ratio [OR]=5.53, 95% confidence interval [CI] 1.48–20.61), cognitive impairment (OR=3.70, 95% CI 1.21–11.31), and dependent functional capacity (OR=11.62, 95% CI 3.38–39.99). Overlap of three evaluated syndromes was found in 24.1%, 7.2%, and 61.3% of subjects with frailty, possible sarcopenia, and malnutrition, respectively. It was characterized by a substantial proportion of female sex, older adults with low educational attainment, diabetes mellitus, hypertension, cognitive impairment, multimorbidity, and dependent functional status. Conclusion Approximately 1 in 30 community-dwelling older outpatients had overlapping frailty, possible sarcopenia, and malnutrition. The condition is associated with TIA and cerebrovascular accident, cognitive impairment, and dependent functional capacity. Standardized screening in community-dwelling older population is necessary. |
| format | Article |
| id | doaj-art-0cbda10f6dd1429d8dd1e34cd18138c8 |
| institution | DOAJ |
| issn | 2508-4798 2508-4909 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Korea Geriatrics Society |
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| series | Annals of Geriatric Medicine and Research |
| spelling | doaj-art-0cbda10f6dd1429d8dd1e34cd18138c82025-08-20T03:07:27ZengKorea Geriatrics SocietyAnnals of Geriatric Medicine and Research2508-47982508-49092025-03-012919110110.4235/agmr.24.01441172Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational StudySiti Setiati0Kuntjoro Harimurti1Ika Fitriana2Noto Dwimartutie3Rahmi Istanti4Muhammad Khifzhon Azwar5I Gusti Putu Suka Aryana6Sri Sunarti7Agus Sudarso8Dina Aprillia Ariestine9Lazuardhi Dwipa10Novira Widajanti11Nur Riviati12Roza Mulyana13Rensa Rensa14Yudo Murti Mupangati15Fatichati Budiningsih16Nina Kemala Sari17 Division of Geriatric Medicine, Department of Internal Medicine, Cipto Mangunkusumo Hospital – Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia Division of Geriatric Medicine, Department of Internal Medicine, Cipto Mangunkusumo Hospital – Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia Division of Geriatric Medicine, Department of Internal Medicine, Cipto Mangunkusumo Hospital – Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia Division of Geriatric Medicine, Department of Internal Medicine, Cipto Mangunkusumo Hospital – Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia Division of Geriatric Medicine, Department of Internal Medicine, Cipto Mangunkusumo Hospital – Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia Division of Geriatric Medicine, Department of Internal Medicine, Cipto Mangunkusumo Hospital – Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Andalas, Padang, Indonesia School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, North Jakarta, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia Department of Internal Medicine, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia Division of Geriatric Medicine, Department of Internal Medicine, Cipto Mangunkusumo Hospital – Faculty of Medicine, Universitas Indonesia, Jakarta, IndonesiaBackground The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap and the associated factors in community-dwelling older outpatients. Methods We collected data from community-dwelling outpatients aged ≥60 years in Indonesian geriatric care centres to conduct this cross-sectional study with bivariate and multivariable analyses. Frailty, possible sarcopenia, and malnutrition diagnoses were based on FRAIL scale, Asian Working Group for Sarcopenia 2019 consensus, and Mini Nutritional Assessment Short Form, respectively. Results The prevalence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients were 13.6%, 45.5%, and 5.3%, respectively. The prevalence of co-occurrence of frailty, possible sarcopenia and malnutrition was 3.3%. It was associated with transient ischemic attack (TIA) and cerebrovascular accident (odds ratio [OR]=5.53, 95% confidence interval [CI] 1.48–20.61), cognitive impairment (OR=3.70, 95% CI 1.21–11.31), and dependent functional capacity (OR=11.62, 95% CI 3.38–39.99). Overlap of three evaluated syndromes was found in 24.1%, 7.2%, and 61.3% of subjects with frailty, possible sarcopenia, and malnutrition, respectively. It was characterized by a substantial proportion of female sex, older adults with low educational attainment, diabetes mellitus, hypertension, cognitive impairment, multimorbidity, and dependent functional status. Conclusion Approximately 1 in 30 community-dwelling older outpatients had overlapping frailty, possible sarcopenia, and malnutrition. The condition is associated with TIA and cerebrovascular accident, cognitive impairment, and dependent functional capacity. Standardized screening in community-dwelling older population is necessary.http://www.e-agmr.org/upload/pdf/agmr-24-0144.pdfcognitive dysfunctionfrailtyindonesiamalnutritionsarcopeniastroke |
| spellingShingle | Siti Setiati Kuntjoro Harimurti Ika Fitriana Noto Dwimartutie Rahmi Istanti Muhammad Khifzhon Azwar I Gusti Putu Suka Aryana Sri Sunarti Agus Sudarso Dina Aprillia Ariestine Lazuardhi Dwipa Novira Widajanti Nur Riviati Roza Mulyana Rensa Rensa Yudo Murti Mupangati Fatichati Budiningsih Nina Kemala Sari Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study Annals of Geriatric Medicine and Research cognitive dysfunction frailty indonesia malnutrition sarcopenia stroke |
| title | Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study |
| title_full | Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study |
| title_fullStr | Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study |
| title_full_unstemmed | Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study |
| title_short | Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study |
| title_sort | co occurrence of frailty possible sarcopenia and malnutrition in community dwelling older outpatients a multicentre observational study |
| topic | cognitive dysfunction frailty indonesia malnutrition sarcopenia stroke |
| url | http://www.e-agmr.org/upload/pdf/agmr-24-0144.pdf |
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