Identification of novel anti-tumor peptides from enzymatic hydrolysis of soy-based tempeh and their mechanism in pancreatic and colorectal cancer cells

Identification of novel anti-tumor peptides from enzymatic hydrolysis of soy-based tempeh and their mechanism in pancreatic and colorectal cancer cells

The aim of this work was to identify peptides in a hydrolysate of soy-based tempeh (SBTE), and determine their antitumor function using bioinformatics and mode cells. The work employed a multi-faceted approach to determine the antitumor activity of SBTE and its derived peptide components against pan...

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Bibliographic Details
Main Authors: Kiki Lukman, Prapanca Nugraha, Nurpudji Astuti Taslim, Nuril Farid Abshori, Elvan Wiyarta, Timothy Sahala Gerardo, Krisanto Tanjaya, Juan Leonardo, Raymond Rubianto Tjandrawinata, Happy Kurnia Permatasari, Fahrul Nurkolis
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Agriculture and Food Research
Subjects:
Tempeh
Soybean
Functional food
Pancreatic cancer
Colorectal cancer
Peptides
Online Access:http://www.sciencedirect.com/science/article/pii/S2666154325004557
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