Synthesis and characterization of glyoxal-crosslinked chitosan with N-amino anthracene succinimide polymers for antimicrobial applications
Abstract This paper presents the synthesis and characterization of a novel chitosan-derivative polymers by using glyoxal as acrosslinker between chitosan and N-amino-9,10-dihydro-anthracene-9,10-α,β-succinamide (AS) under our conditions. The generated polymers were characterized using X-ray diffract...
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| Language: | English |
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BMC
2025-05-01
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| Series: | BMC Chemistry |
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| Online Access: | https://doi.org/10.1186/s13065-025-01505-2 |
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| author | Ahmed G. Taha A. M. Hezma |
| author_facet | Ahmed G. Taha A. M. Hezma |
| author_sort | Ahmed G. Taha |
| collection | DOAJ |
| description | Abstract This paper presents the synthesis and characterization of a novel chitosan-derivative polymers by using glyoxal as acrosslinker between chitosan and N-amino-9,10-dihydro-anthracene-9,10-α,β-succinamide (AS) under our conditions. The generated polymers were characterized using X-ray diffraction (XRD) and infrared spectroscopy (IR). The results indicate the successful formation of new polymer structures with unique properties. The antimicrobial activity of Chs-Gly-AS and its modified derivatives was evaluated using the cup diffusion agar method, showing enhanced inhibition against bacteria and fungi. The results demonstrate promising antimicrobial efficacy, suggesting the potential use of these polymers in antimicrobial applications. |
| format | Article |
| id | doaj-art-0cb8a339a95548448ee199c758e096cb |
| institution | OA Journals |
| issn | 2661-801X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Chemistry |
| spelling | doaj-art-0cb8a339a95548448ee199c758e096cb2025-08-20T02:33:31ZengBMCBMC Chemistry2661-801X2025-05-0119111410.1186/s13065-025-01505-2Synthesis and characterization of glyoxal-crosslinked chitosan with N-amino anthracene succinimide polymers for antimicrobial applicationsAhmed G. Taha0A. M. Hezma1Department of Chemistry, Faculty of Science, South Valley UniversitySpectroscopy Department, Physics Research Institute, National Research CentreAbstract This paper presents the synthesis and characterization of a novel chitosan-derivative polymers by using glyoxal as acrosslinker between chitosan and N-amino-9,10-dihydro-anthracene-9,10-α,β-succinamide (AS) under our conditions. The generated polymers were characterized using X-ray diffraction (XRD) and infrared spectroscopy (IR). The results indicate the successful formation of new polymer structures with unique properties. The antimicrobial activity of Chs-Gly-AS and its modified derivatives was evaluated using the cup diffusion agar method, showing enhanced inhibition against bacteria and fungi. The results demonstrate promising antimicrobial efficacy, suggesting the potential use of these polymers in antimicrobial applications.https://doi.org/10.1186/s13065-025-01505-2ChitosanGlyoxalN-amino-9,10-dihydro-anthracene-9,10-α,β-succinamidPolymersXRDIR |
| spellingShingle | Ahmed G. Taha A. M. Hezma Synthesis and characterization of glyoxal-crosslinked chitosan with N-amino anthracene succinimide polymers for antimicrobial applications BMC Chemistry Chitosan Glyoxal N-amino-9,10-dihydro-anthracene-9,10-α,β-succinamid Polymers XRD IR |
| title | Synthesis and characterization of glyoxal-crosslinked chitosan with N-amino anthracene succinimide polymers for antimicrobial applications |
| title_full | Synthesis and characterization of glyoxal-crosslinked chitosan with N-amino anthracene succinimide polymers for antimicrobial applications |
| title_fullStr | Synthesis and characterization of glyoxal-crosslinked chitosan with N-amino anthracene succinimide polymers for antimicrobial applications |
| title_full_unstemmed | Synthesis and characterization of glyoxal-crosslinked chitosan with N-amino anthracene succinimide polymers for antimicrobial applications |
| title_short | Synthesis and characterization of glyoxal-crosslinked chitosan with N-amino anthracene succinimide polymers for antimicrobial applications |
| title_sort | synthesis and characterization of glyoxal crosslinked chitosan with n amino anthracene succinimide polymers for antimicrobial applications |
| topic | Chitosan Glyoxal N-amino-9,10-dihydro-anthracene-9,10-α,β-succinamid Polymers XRD IR |
| url | https://doi.org/10.1186/s13065-025-01505-2 |
| work_keys_str_mv | AT ahmedgtaha synthesisandcharacterizationofglyoxalcrosslinkedchitosanwithnaminoanthracenesuccinimidepolymersforantimicrobialapplications AT amhezma synthesisandcharacterizationofglyoxalcrosslinkedchitosanwithnaminoanthracenesuccinimidepolymersforantimicrobialapplications |