The secreted proteases aur, scpA, sspA and sspB suppress the virulence of Staphylococcus aureus USA300 by shaping the extracellular proteome

Surface-located and secreted virulence factors of the Gram-positive bacterial pathogen Staphylococcus aureus are key drivers for infection of the human host. Proteolytic enzymes may contribute to virulence by breaking primary barriers and host immune defenses. Therefore, the objective of our study w...

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Bibliographic Details
Main Authors: Xiaofang Li, Sandra Maaß, Borja Ferrero-Bordera, Zhichao Zhang, Min Wang, Eric Sietsema, Lei Liu, Madeleine Divinagracia, Jan Maarten van Dijl, Girbe Buist
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
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Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2514790
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