BI 1015550 Improves Silica-Induced Silicosis and LPS-Induced Acute Lung Injury in Mice

BI 1015550 Improves Silica-Induced Silicosis and LPS-Induced Acute Lung Injury in Mice

Silicosis is an interstitial lung disease (ILD) caused by prolonged inhalation of silica particles. Acute lung injury (ALI) is a critical clinical syndrome involving bilateral lung infiltration and acute hypoxic respiratory failure. However, there is currently no effective treatment for these two di...

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Bibliographic Details
Main Authors: Yuming Liu, Jing Zhang, Yayue Hu, Zhigang Liu, Zhongyi Yang, Ran Jiao, Xueze Liu, Xiaohe Li, Feng Sang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
Subjects:
BI 1015550
PDE4B
cAMP
silicosis
acute lung injury
Online Access:https://www.mdpi.com/1420-3049/30/6/1311
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